Evidence map›Paper›PMID 34019387›Full record

ArticleACS chemical neuroscience2021

Development of New Benzylpiperazine Derivatives as σ

Giuseppe Romeo, Federica Bonanno, Lisa L Wilson, Emanuela Arena, Maria N Modica, Valeria Pittalà, Loredana Salerno, Orazio Prezzavento, Jay P McLaughlin, Sebastiano Intagliata

Open access · hybridAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Sphingoid Bases Regulate the Sigma-1 Receptor-Sphingosine andInternational journal of molecular sciences · 2023
    Article
  5. Article
  6. UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Giuseppe RomeoDepartment of Drug and Health Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.ORCID 0000-0003-2160-4164
Federica BonannoDepartment of Drug and Health Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.
Lisa L WilsonDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Emanuela ArenaDepartment of Drug and Health Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.
Maria N ModicaDepartment of Drug and Health Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.ORCID 0000-0002-6350-931X
Valeria PittalàDepartment of Drug and Health Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.ORCID 0000-0003-1856-0308
Loredana SalernoDepartment of Drug and Health Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.ORCID 0000-0001-6458-3717
Orazio PrezzaventoDepartment of Drug and Health Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.ORCID 0000-0002-3521-264X
Jay P McLaughlinDepartment of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States.
Sebastiano IntagliataDepartment of Drug and Health Sciences, University of Catania, viale A. Doria 6, 95125 Catania, Italy.ORCID 0000-0002-0201-1745
University of Catania · ITUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

σ-1 receptors (σ

Indexed as

Receptors, sigmaAnalgesicsAnimalsHyperalgesiaLigandsMiceSigma-1 ReceptorStructure-Activity RelationshipAnalgesicsLigandsReceptors, sigmaSigma-1 ReceptoranalgesiaBenzylpiperazinesneuropathic painσ-1 antagonistσ receptors

Identifiers

PMID34019387
PMCPMC8291485
OpenAlexW3162134450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.