ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2021
Computed tomography features predictive of intra-abdominal hypertension in acute necrotizing pancreatitis: A prospective study.
Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Intra-abdominal Hypertension Is a Strong Predictor of Mortality and Poor Clinical Outcome in Severe Acute Pancreatitis.Digestive diseases and sciences · 2025Pooled it
- The accuracy of a new noninvasive approach using physical examination combined with ultrasonography to detect intraabdominal hypertension.Scientific reports · 2025Article
- Abdominal compartment syndrome: what radiologist needs to know.La Radiologia medica · 2023Review
- Intra-abdominal hypertension and abdominal compartment syndrome in acute pancreatitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023Review
- Evaluation of Intra-Abdominal Hypertension Parameters in Patients with Acute Pancreatitis.Life (Basel, Switzerland) · 2023Article
- A novel clinical prediction model of severity based on red cell distribution width, neutrophil-lymphocyte ratio and intra-abdominal pressure in acute pancreatitis in pregnancy.BMC pregnancy and childbirth · 2023Article
- Evaluation of Inflammatory Infiltration in the Retroperitoneal Space of Acute Pancreatitis Using Computer Tomography and Its Correlation with Clinical Severity.Contrast media & molecular imaging · 2023Article
- Abdominal Compartment Syndrome in Acute Pancreatitis: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
- Intra-Abdominal Hypertension: A Systemic Complication of Severe Acute Pancreatitis.Medicina (Kaunas, Lithuania) · 2022Review
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5 authors at 1 institution in 1 country.
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Abstract
backgroundIntra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) in acute pancreatitis (AP) are associated with development and worsening of organ failures and poor prognosis. Limited studies suggest that contrast-enhanced computed tomography (CECT) can predict the presence of IAH/ACS. We aimed to study clinical profile of patients with AP and IAH and identify predictive factors of IAH on CECT abdomen.
methodsConsecutive patients admitted with moderately severe and severe acute pancreatitis (SAP) were recruited. Clinical and radiological data were recorded prospectively. Intra-abdominal pressure was measured via a urinary catheter to document the presence of IAH/ACS. CECT abdomen was done within the first week of admission and various features that may predict the presence of IAH were studied.
resultsThirty-seven patients (24 SAP) (mean age: 39.78 ± 13.43 years and 67.6% males) with AP were studied. The most common etiology was alcohol (37.7%). IAH developed in 54.05% of patients; patients with IAH had significantly higher bedside index of severity in AP (BISAP), Acute Physiologic Assessment and Chronic Health Evaluation II (APACHE II) score, persistent acute lung injury (ALI), persistent acute kidney injury (AKI), persistent cardiovascular failure (CVSF), intensive care unit (ICU) stay, and mortality. Among the CT predictors, patients with IAH more commonly had moderate-gross ascites (60% vs. 23.5%, p-value - 0.026), a pancreatic necrosis of > 50% (50% vs. 17.6%, p-value - 0.04), and a round belly sign (RBS) (50% vs. 5.9%, p-value 0.03). On multivariate analysis, only RBS was predictive of IAH (odds ratio 12.6, 95% confidence interval 1.3-124.2, p-value 0.03). The sensitivity, specificity, positive predictive value, and negative predictive value for RBS were 50%, 94.12%, 90.9%, and 61.54%, respectively.
conclusionPresence of RBS, moderate-gross ascites, and pancreatic necrosis of > 50% on CECT can predict the presence of IAH in these groups of patients.
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