Evidence map›Paper›PMID 34019228›Full record

ArticlePhysical and engineering sciences in medicine2021

The first real-time intrafraction target position monitoring in pancreas SBRT on an Elekta linear accelerator.

Sankar Arumugam, Darren Pavey, Andrew Oar, Lois Holloway, Mark Sidhom, Mark Lee

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Article in Physical and engineering sciences in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sankar ArumugamDepartment of Medical Physics, Liverpool and Macarthur Cancer Therapy Centres and Ingham Institute, Liverpool, Sydney, NSW, Australia. Sankar.Arumugam@health.nsw.gov.au.
Darren PaveyDepartment of Radiology, Liverpool and Macarthur Cancer Therapy Centres and Ingham Institute, Liverpool, Sydney, NSW, Australia.
Andrew OarRadiation Oncology Centre, Gold Coast University Hospital, Southport, QLD, Australia.
Lois HollowayDepartment of Medical Physics, Liverpool and Macarthur Cancer Therapy Centres and Ingham Institute, Liverpool, Sydney, NSW, Australia.
Mark SidhomDepartment of Radiation Oncology, Liverpool and Macarthur Cancer Therapy Centres, Liverpool, Sydney, NSW, Australia.
Mark LeeDepartment of Radiation Oncology, Liverpool and Macarthur Cancer Therapy Centres, Liverpool, Sydney, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To perform implanted fiducial based real-time target position monitoring in pancreas stereotactic body radiotherapy (SBRT) using the x-ray imaging system available in a Elekta linear accelerator. An in-house system was developed and clinically utilised for real-time target position monitoring of pancreas SBRT delivery. The developed system was used for the target position monitoring of a pancreas cancer patient treated in free breathing treatment within the study entitled 'Mfolfirinox And STEreotactic Radiotherapy for Patients with Locally Advanced paNcreas cancer (MASTERPLAN): a feasibility study' (ACTRN 12617001642370) consisting of five treatment fractions. The clinical efficacy of the system was studied by performing a retrospective cumulative dose assessment of delivered dose using observed position deviations. The developed system identified two events of baseline shifts in target position that exceeded the accepted tolerance level of ± 3 mm from reference planned position. The retrospective dose assessment study showed that if the position deviations were not detected and corrected for, the maximum dose to duodenum would have increased from 34.6 to 38.8 Gy. The first real-time position monitoring in pancreas SBRT on an Elekta linear accelerator was successfully performed. The developed system was shown to improve the safety and accuracy of SBRT delivery.

Indexed as

RadiosurgeryHumansPancreasParticle AcceleratorsRadiotherapy Planning, Computer-AssistedRetrospective StudiesDosimetric impactOnline position monitoringPosition deviationSBRT

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.