Evidence map›Paper›PMID 34018925›Full record

ArticleeLife2021

Thirst interneurons that promote water seeking and limit feeding behavior in

Dan Landayan, Brian P Wang, Jennifer Zhou, Fred W Wolf

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Connectomic mapping of pharyngeal and gut sensory circuits in adultbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Body fluid regulation.Current opinion in neurobiology · 2025
    Review
  10. Article
  11. Article
  12. Gut-Brain Dialogues in Fruit Fly (Current drug targets · 2025
    Review
  13. Article
  14. Thirst-driven hygrosensory suppression promotes water seeking inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dan LandayanQuantitative and Systems Biology Graduate Program, UC, Merced, United States.
Brian P WangQuantitative and Systems Biology Graduate Program, UC, Merced, United States.
Jennifer ZhouDepartment of Molecular and Cell Biology, UC, Merced, United States.
Fred W WolfQuantitative and Systems Biology Graduate Program, UC, Merced, United States.ORCID 0000-0002-4230-194X
University of California, Merced · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thirst is a motivational state that drives behaviors to obtain water for fluid homeostasis. We identified two types of central brain interneurons that regulate thirsty water seeking in

Indexed as

DrinkingFeeding BehaviorHungerThirstAnimalsAnimals, Genetically ModifiedBrainDrosophila melanogasterDrosophila ProteinsGABAergic NeuronsInterneuronsNeural InhibitionNeuropeptide YOligopeptidesReceptors, NeuropeptideAstA-R2 protein, DrosophilaDrosophila ProteinsNeuropeptide YOligopeptidesReceptors, NeuropeptideAstAD. melanogastergeneticsgenomicsneural circuitsneuroscienceNPFseekingThirst

Identifiers

PMID34018925
PMCPMC8139827
OpenAlexW3161424202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.