Evidence map›Paper›PMID 34018905›Full record

ArticleRedox report : communications in free radical research2021

Ameliorative effects of

Firdaus Kausar, Muzafar Ahmad Rather, Showkeen Muzamil Bashir, Rana M Alsaffar, Showkat Ul Nabi, Sofi Imtiyaz Ali, Pankaj Goswami, Ansar Ahmad, Summya Rashid, Adil Farooq Wali

Open access · goldAbstract read
In one paragraph

Article in Redox report : communications in free radical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Ameliorative effects ofJournal of traditional and complementary medicine · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Therapeutic Effect ofClinical medicine insights. Endocrinology and diabetes · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Firdaus KausarDepartment of Ilmul Advia, Regional Research Institute of Unani Medicine, Srinagar, Jammu & Kashmir, India.
Muzafar Ahmad RatherBiochemistry and Molecular Biology Lab., Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry, Sher e Kashmir University of Agriculture Science and Technology-Kashmir (SKUAST-K), Srinagar, Jammu & Kashmir, India.
Showkeen Muzamil BashirBiochemistry and Molecular Biology Lab., Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry, Sher e Kashmir University of Agriculture Science and Technology-Kashmir (SKUAST-K), Srinagar, Jammu & Kashmir, India.
Rana M AlsaffarDepartment of Pharmacology & Toxicology, College of Pharmacy Girls Section, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Showkat Ul NabiDivision of Veterinary Clinical Medicine Ethics and Jurisprudence, Faculty of Veterinary Sciences & Animal Husbandry, Sher e Kashmir University of Agriculture Science and Technology-Kashmir (SKUAST-K), Srinagar, Jammu & Kashmir, India.
Sofi Imtiyaz AliBiochemistry and Molecular Biology Lab., Division of Veterinary Biochemistry, Faculty of Veterinary Sciences & Animal Husbandry, Sher e Kashmir University of Agriculture Science and Technology-Kashmir (SKUAST-K), Srinagar, Jammu & Kashmir, India.
Pankaj GoswamiDivision of Veterinary Pathology, Faculty of Veterinary Sciences & Animal Husbandry, Sher e Kashmir University of Agriculture Science and Technology-Kashmir (SKUAST-K), Srinagar, Jammu & Kashmir, India.
Ansar AhmadDepartment of Ilmul Advia, Regional Research Institute of Unani Medicine, Srinagar, Jammu & Kashmir, India.
Summya RashidDepartment of Pharmacology & Toxicology, College of Pharmacy Girls Section, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Adil Farooq WaliDepartment of Pharmaceutical Chemistry, RAK College of Pharmaceutical Sciences, RAK Medical and Health Science University, Ras Al Khaimah, UAE.ORCID https://orcid.org/0000-0003-1555-2820
Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir · INPrince Sattam Bin Abdulaziz University · SARegional Research Institute of Unani Medicine · INRas al-Khaimah Medical and Health Sciences University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe current study was designed to examine the therapeutic role of hydroalcoholic extract of

methodsPCOS rats were treated with CRE (280 mg/kg), PGE (140 mg/kg) or CRE + PGE p.o. for 3 weeks. Vaginal smears for phase of estrous cycle determination, serum levels of sex androgens, lipid profile, oxidative stress parameters and histopathology of ovarian tissues were investigated.

resultsDiestrous cycle days treated with CRE (group III) or PGE (group IV) decreased significantly (

conclusionThe study demonstrated that the CRE and PGE either alone or in combination hold a significant effect in letrozole induced PCOS rat models and could be useful in the management of reproductive and metabolic disorders related to PCOS.

Indexed as

CuscutaPolycystic Ovary SyndromeAnimalsDisease Models, AnimalFemaleLetrozoleRatsRats, WistarLetrozolediestrous cyclehistopathological examinationhydroalcoholic extractMetabolic disorders

Identifiers

PMID34018905
PMCPMC8158284
OpenAlexW3163396248

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.