Evidence map›Paper›PMID 34018815›Full record

ArticleCirculation research2021

CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.

Yiangos Psaras, Francesca Margara, Marcelo Cicconet, Alexander J Sparrow, Giuliana G Repetti, Manuel Schmid, Violetta Steeples, Jonathan A L Wilcox, Alfonso Bueno-Orovio, Charles S Redwood and 6 more

Open access · hybridAbstract readVideo-Audio Media
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 57 citations in OpenAlex.

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  19. Comparing the effects of chemical CaJournal of molecular and cellular cardiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 4 countries.

Yiangos Psaras *Division of Cardiovascular Medicine, Radcliffe Department of Medicine (Y.P., F.M., A.J.S., M.S., V.S., C.S.R., H.C.W., P.R., C.N.T.), University of Oxford, United Kingdom.
Francesca Margara *Computer Science (F.M., A.B.-O., B.R.), University of Oxford, United Kingdom.
Marcelo Cicconet
Alexander J Sparrow
Giuliana G RepettiGenetics (G.G.R., J.A.L.W., J.G.S., C.E.S., C.N.T.), Harvard Medical School, Boston, MA.
Manuel Schmid
Violetta Steeples
Jonathan A L WilcoxGenetics (G.G.R., J.A.L.W., J.G.S., C.E.S., C.N.T.), Harvard Medical School, Boston, MA.
Alfonso Bueno-OrovioComputer Science (F.M., A.B.-O., B.R.), University of Oxford, United Kingdom.
Charles S Redwood
Hugh C WatkinsWellcome Centre for Human Genetics (H.C.W., C.N.T.), University of Oxford, United Kingdom.
Paul RobinsonDivision of Cardiovascular Medicine, Radcliffe Department of Medicine (Y.P., F.M., A.J.S., M.S., V.S., C.S.R., H.C.W., P.R., C.N.T.), University of Oxford, United Kingdom.
Blanca RodriguezComputer Science (F.M., A.B.-O., B.R.), University of Oxford, United Kingdom.
Jonathan G SeidmanGenetics (G.G.R., J.A.L.W., J.G.S., C.E.S., C.N.T.), Harvard Medical School, Boston, MA.
Christine E SeidmanGenetics (G.G.R., J.A.L.W., J.G.S., C.E.S., C.N.T.), Harvard Medical School, Boston, MA.
Christopher N ToepferDivision of Cardiovascular Medicine, Radcliffe Department of Medicine (Y.P., F.M., A.J.S., M.S., V.S., C.S.R., H.C.W., P.R., C.N.T.), University of Oxford, United Kingdom.
Harvard University · USCentre for Human Genetics · GBJohn Radcliffe Hospital · GBBrigham and Women's Hospital · USQueen Margaret University · GBSchmid (Germany) · DEScience Oxford · GBUniversidad Nacional Experimental Simón Rodríguez · VE

Funding

Defining Pathways from Gene Mutation to Heart FailureR01HL080494 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI CHEN, CHRISTOPHER S, SEIDMAN, CHRISTINE E · 2005 to 2024
$9.4M
British Heart Foundation CH/1992001/6764British Heart Foundation FS/17/22/32644British Heart Foundation RE/18/3/34214British Heart Foundation RG/12/16/29939Howard Hughes Medical InstituteNational Centre for the Replacement, Refinement and Reduction of Animals in Research NC/P001076/1NHLBI NIH HHS R01 HL080494Wellcome Trust 206466Wellcome Trust 206466/Z/17/ZWellcome Trust 214290/Z/18/Z
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AlgorithmsCalcium SignalingHigh-Throughput Screening AssaysImage Processing, Computer-AssistedMicroscopy, FluorescenceAnimalsAutomation, LaboratoryCalciumCells, CulturedGuinea PigsHumansInduced Pluripotent Stem CellsKineticsMutation, MissenseMyocytes, CardiacTroponin ICalciumTNNI3 protein, humanTroponin Icalciumcardiomyopathy, hypertrophicinduced pluripotent stem cellsmyocytes, cardiacphotobleaching

Identifiers

PMID34018815
PMCPMC8260473
OpenAlexW3163682241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.