ArticleAmerican journal of primatology2021
The marmoset as an important primate model for longitudinal studies of neurocognitive aging.
Article in American journal of primatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Review
- Brain/MINDS Marmoset Brain Atlas 2.0: Population Cortical Parcellation With Multi-Modal Templates.Scientific data · 2026Article
- The Visual Umwelt of primates and Hippocampal Representations of Space.Hippocampus · 2026Review
- Challenges and opportunities of psychological aging research.European journal of ageing · 2025Review
- Article
- Beyond Transgenic Mice: Emerging Models and Translational Strategies in Alzheimer's Disease.International journal of molecular sciences · 2025Review
- Marmosets as model systems for the study of Alzheimer's disease and related dementias: Substantiation of physiological tau 3R and 4R isoform expression and phosphorylation.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Animal models of Alzheimer's disease: Current strategies and new directions.Zoological research · 2024Review
- The importance of social behavior in nonhuman primate studies of aging: A mini-review.Neuroscience and biobehavioral reviews · 2023Review
- Cognitive development from infancy to young adulthood in common marmosets (Callithrix jacchus): Effect of age, sex, and hormones on learning and affective state.Developmental psychobiology · 2023Article
- Survival rates and mortality risks of Plecturocebus cupreus at the California National Primate Research Center.American journal of primatology · 2023Article
- Neuronal vulnerability to brain aging and neurodegeneration in cognitively impaired marmoset monkeys (Callithrix jacchus).Neurobiology of aging · 2023Article
- Potential trade-off between olfactory and visual discrimination learning in common marmosets (Callithrix jacchus): Implications for the assessment of age-related cognitive decline.American journal of primatology · 2022Article
- Sex differences in cognitive aging: a 4-year longitudinal study in marmosets.Neurobiology of aging · 2022Article
- Nonhuman primates at the intersection of aging biology, chronic disease, and health: An introduction to the American Journal of Primatology Special Issue on aging, cognitive decline, and neuropathology in nonhuman primates.American journal of primatology · 2021Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Age-related cognitive decline has been extensively studied in humans, but the majority of research designs are cross-sectional and compare across younger and older adults. Longitudinal studies are necessary to capture variability in cognitive aging trajectories but are difficult to carry out in humans and long-lived nonhuman primates. Marmosets are an ideal primate model for neurocognitive aging as their naturally short lifespan facilitates longitudinal designs. In a longitudinal study of marmosets tested on reversal learning starting in middle-age, we found that, on average, the group of marmosets declined in cognitive performance around 8 years of age. However, we found highly variable patterns of cognitive aging trajectories across individuals. Preliminary analyses of brain tissues from this cohort also show highly variable degrees of neuropathology. Future work will tie together behavioral trajectories with brain pathology and provide a window into the factors that predict age-related cognitive decline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.