Evidence map›Paper›PMID 34018481›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2021

The potential for vaccination-induced herd immunity against the SARS-CoV-2 B.1.1.7 variant.

David Hodgson, Stefan Flasche, Mark Jit, Adam J Kucharski, CMMID COVID-19 Working Group, Centre for Mathematical Modelling of Infectious Disease (CMMID) COVID-19 Working Group

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Reformulating the susceptible-infectious-removed model in terms of the number of detected cases: well-posedness of the observational model.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022
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  17. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  18. Achieving and sustaining herd immunity to SARS-CoV-2.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  19. Increased transmissibility and global spread of SARS-CoV-2 variants of concern as at June 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David HodgsonCentre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Stefan FlascheCentre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Mark JitCentre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Adam J KucharskiCentre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
CMMID COVID-19 Working GroupCentre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Centre for Mathematical Modelling of Infectious Disease (CMMID) COVID-19 Working Group

Funding

CRCNS: Deep Neural Network Approaches for Closed-Loop Deep Brain StimulationR01NS110424 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RICHARDSON, ROBERT MARK, TURNER, ROBERT STERLING · 2018 to 2020
$673k
Medical Research Council MC_PC_19065Medical Research Council MR/P014658/1Medical Research Council MR/S003975/1Medical Research Council MR/V027956/1NINDS NIH HHS R01 NS110424Wellcome Trust
6 · The paper itself

Abstract

We assess the feasibility of reaching the herd immunity threshold against SARS-CoV-2 through vaccination, considering vaccine effectiveness (VE), transmissibility of the virus and the level of pre-existing immunity in populations, as well as their age structure. If highly transmissible variants of concern become dominant in areas with low levels of naturally-acquired immunity and/or in populations with large proportions of < 15 year-olds, control of infection without non-pharmaceutical interventions may only be possible with a VE ≥ 80%, and coverage extended to children.

Indexed as

COVID-19SARS-CoV-2ChildHumansImmunity, HerdVaccinationHerd ImmunitySARS-CoV-2seroprevalencevaccination

Identifiers

PMID34018481
PMCPMC8138959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.