Evidence map›Paper›PMID 34017897›Full record

ReviewAIMS public health2021

The role of trust in HPV vaccine uptake among racial and ethnic minorities in the United States: a narrative review.

Nicole Harrington, Yuku Chen, Alana M O'Reilly, Carolyn Y Fang

Abstract readReview
In one paragraph

Review in AIMS public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Co-creating HPV Vaccination Messages for Rural Washington: Application of a Boot Camp Translation Approach.Health education & behavior : the official publication of the Society for Public Health Education · 2026
    Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Exploring Trusted Sources of HPV Vaccine Information Among Mexican American Parents in El Paso, Texas.International journal of environmental research and public health · 2025
    Article
  13. Article
  14. Review
  15. COVID-19 clinical trial participation and awareness in Texas.Human vaccines & immunotherapeutics · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicole HarringtonImmersion Science Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
Yuku ChenCancer Prevention & Control Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
Alana M O'ReillyMolecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
Carolyn Y FangCancer Prevention & Control Program, Fox Chase Cancer Center, Philadelphia, PA, USA.

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Dietmar J Kappes · 1985 to 2026
$138.8M
TUFCCC/HC Regional Comprehensive Cancer Health PartnershipU54CA221705 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI Yin Tan · 2018 to 2026
$16.3M
TUFCCC/HC Regional Comprehensive Cancer Health PartnershipU54CA221704 · NCI · HUNTER COLLEGE · PI Ming-Chin Yeh · 2018 to 2026
$10.6M
NCI NIH HHS P30 CA006927NCI NIH HHS U54 CA221704NCI NIH HHS U54 CA221705
6 · The paper itself

Abstract

Despite the clinically proven benefits of the human papillomavirus (HPV) vaccine in preventing cervical and other HPV-associated cancers, vaccination coverage has been suboptimal among adolescents and young adults in the United States (US), particularly among racial and ethnic minority adolescents. Historical legacies, combined with current racial/ethnic disparities in healthcare, may contribute to suboptimal uptake and completion of the HPV vaccine in part through differing levels of trust in doctors and healthcare institutions. The purpose of this narrative review was to characterize trust and its role in decision making about HPV vaccine uptake among US racial and ethnic minorities. We conducted a literature search using the PubMed database, and our search terms yielded 1176 articles. We reviewed 41 full-text articles for eligibility and included 20 articles in this review. These studies used varied measures of trust or mistrust and assessed trust in not only doctors/healthcare providers, but also other sources including pharmaceutical companies, media, and clergy. Our review findings revealed generally high levels of trust in doctors and healthcare providers, but less so in pharmaceutical companies. Mistrust of either healthcare providers, government agencies or pharmaceutical companies was consistently associated with less favorable attitudes and lower vaccine uptake. The downstream effects of mistrust may occur through selected health beliefs regarding the perceived efficacy and safety of the vaccine. Minority groups were more likely to report trust in family members, religious organizations, and media sources compared to their white counterparts. Decision making about vaccine uptake is a multilayered process that involves comparing the perceived benefits of the vaccine against its perceived risks. Understanding how trusted sources can effectively harness the tools of social and traditional media to increase knowledge and awareness may help combat misinformation about the HPV vaccine and improve engagement with diverse communities.

Indexed as

human papillomavirusracial/ethnic minoritiestrustUnited Statesvaccination

Identifiers

PMID34017897
PMCPMC8116180

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.