Evidence map›Paper›PMID 34017833›Full record

ArticleFrontiers in cell and developmental biology2021

Sheng Xia, Wei Yu, Heather Menden, Scott T Younger, Venkatesh Sampath

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sheng XiaDepartment of Pediatrics, Children's Mercy Kansas City, MO, United States.
Wei YuDepartment of Pediatrics, Children's Mercy Kansas City, MO, United States.
Heather MendenDepartment of Pediatrics, Children's Mercy Kansas City, MO, United States.
Scott T YoungerCenter for Pediatric Genomic Medicine, Children's Mercy Kansas City, MO, United States.
Venkatesh SampathDepartment of Pediatrics, Children's Mercy Kansas City, MO, United States.
Children's Mercy Hospital · US

Funding

Inflammatory Angiogenesis in the LungR01HL128374 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI SAMPATH, VENKATESH · 2015 to 2020
$1.8M
NHLBI NIH HHS R01 HL128374
6 · The paper itself

Abstract

The innate immune response of pulmonary endothelial cells (EC) to lipopolysaccharide (LPS) induces Forkhead box protein C2 (FOXC2) activation through Toll Like Receptor 4 (TLR4). The mechanisms by which FOXC

Indexed as

autoregulationendotheliumFOXC2lungsepsis

Identifiers

PMID34017833
PMCPMC8129010
OpenAlexW3158307719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.