ArticleAmerican journal of translational research2021
The application value of oXiris-endotoxin adsorption in sepsis.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Extracorporeal Blood Purification with the oXiris® Filter for Patients with Sepsis and Hyperinflammatory Conditions: The Asia-Pacific oXiris Expert Meeting 2024 Consensus Statements.Blood purification · 2025Guideline
- Continuous renal replacement therapy with the adsorptive oXiris filter may be associated with the lower 28-day mortality in sepsis: a systematic review and meta-analysis.Critical care (London, England) · 2023Pooled it
- Association of oXiris Hemoadsorption with Inflammatory, Hemodynamic, Respiratory, and Organ Dysfunction Parameters in Patients with Sepsis and Septic Shock in the Intensive Care Unit: A Retrospective Comparative Cohort Study.Life (Basel, Switzerland) · 2026Article
- The "cytokine storm" in infection and sepsis: win the battle but lose the war.Military Medical Research · 2026Review
- Use of Oxiris membrane in real-world clinical practice in critical care patients: a multicenter observational study.Journal of anesthesia, analgesia and critical care · 2025Article
- Efficacy and prognostic analysis of the oXiris® filter in sepsis-associated acute kidney injury.International urology and nephrology · 2025Article
- [Severe malnutrition during pregnancy complicated with acute pyelonephritis causing sepsis, refractory septic shock and multiple organ failure: A case report].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Article
- ECPR combined with CRRT successfully rescues a patient who experienced sudden cardiac arrest for 152 minutes: A case report.Medicine · 2025Article
- Continuous renal replacement therapy with adsorbing filter oXiris in the treatment of sepsis associated acute kidney injury: a single-center retrospective observational study.BMC nephrology · 2024Observational
- Effects of OxirisInternational journal of molecular sciences · 2024Article
- Continuous veno-venous hemofiltration with oXiris hemofilters for the treatment of Fournier's gangrene: A case report series.Heliyon · 2024Article
- Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of personalized medicine · 2024Review
- Continuous renal replacement therapy with oXirisWorld journal of clinical cases · 2023Article
- Effect of Continuous Renal Replacement Therapy with the oXiris Hemofilter on Critically Ill Patients: A Narrative Review.Journal of clinical medicine · 2022Review
- Soluble ST2 Is a Sensitive and Specific Biomarker for Fulminant Myocarditis.Journal of the American Heart Association · 2022Article
- Application of oXiris-continuous hemofiltration adsorption in patients with sepsis and septic shock: A single-centre experience in China.Frontiers in public health · 2022Article
- Evaluation of the Oxiris Membrane in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support: Study Protocol for a Single Center, Single-Blind, Randomized Controlled Trial.Frontiers in cardiovascular medicine · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study explored and analyzed the application value of oXiris- endotoxin adsorption technology in patients with sepsis.
methods23 sepsis patients hospitalized from January 2018 to September 2019 in our ICU center and received oxiris-endotoxin adsorption were enrolled as the observation group, and another 30 sepsis patients hospitalized during the same period were selected as the control group who treated with routine continuous renal replacement therapy (CRRT). The heart rate, respiratory rate, norepinephrine (NE) dosage, lactic acid, procalcitonin (PCT), urine volume, and sofa scores that evaluate organ failure after systemic infection, as well as ICU stay, organ support duration, and incidence of cardiovascular events were compared between the two groups before and after treatment.
resultsThe heart rate, respiratory rate and NE dosage of the two groups post-treatment were dramatically lower than those pre-treatment (
conclusioncompared with the traditional CRRT technology, the oXiris membrane based CRRT technology can effectively improve the hemodynamic indicators of patients with sepsis, reduce the level of inflammation, and improve the metabolic function of body, thereby improving the patients' organ function. It has good clinical application value in patients with sepsis.
Indexed as
Identifiers
34017574PMC8129347W3160662541What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.