Evidence map›Paper›PMID 34017534›Full record

ArticleAmerican journal of translational research2021

A comparison of the multimodal magnetic resonance imaging features of brain metastases vs. high-grade gliomas.

Jinlai Liu, Hainian Han, Yan Xu, Yan Jin, Fapeng Ma, Jiancheng Mu, Yupeng Wang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jinlai LiuDepartment of Radiology, The Second People's Hospital of Jiaozuo (First Affiliated Hospital of He'nan Polytechnic University) Jiaozuo, He'nan Province, China.
Hainian HanDepartment of Radiology, The Second People's Hospital of Jiaozuo (First Affiliated Hospital of He'nan Polytechnic University) Jiaozuo, He'nan Province, China.
Yan XuDepartment of Radiology, The Second People's Hospital of Jiaozuo (First Affiliated Hospital of He'nan Polytechnic University) Jiaozuo, He'nan Province, China.
Yan JinDepartment of Radiology, The Second People's Hospital of Jiaozuo (First Affiliated Hospital of He'nan Polytechnic University) Jiaozuo, He'nan Province, China.
Fapeng MaDepartment of Radiology, The Second People's Hospital of Jiaozuo (First Affiliated Hospital of He'nan Polytechnic University) Jiaozuo, He'nan Province, China.
Jiancheng MuDepartment of Radiology, The Second People's Hospital of Jiaozuo (First Affiliated Hospital of He'nan Polytechnic University) Jiaozuo, He'nan Province, China.
Yupeng WangDepartment of Radiology, The Second People's Hospital of Jiaozuo (First Affiliated Hospital of He'nan Polytechnic University) Jiaozuo, He'nan Province, China.
Jiaozuo University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to explore the multimodal magnetic resonance imaging (MRI) features of brain metastases and high-grade brain gliomas.

methodsFifty patients with brain metastases and 28 patients with high-grade gliomas treated in the neurosurgery department of our hospital were selected for this study. All patients underwent routine MRI, diffusion tensor imaging, and perfusion-weighted magnetic resonance imaging. The average diffusion coefficient (ADC), fractional anisotropy (FA), regional cerebral blood flow (rCBF), and regional cerebral blood volume (rCBV) in the tumor parenchyma, peritumoral edema area, and the contralateral normal cerebral white matter were compared between the patients with brain metastases and the patients with high-grade brain gliomas.

resultsThere were differences in the degree of peritumoral edema between the two groups of patients (P = 0.017). Compared with the patients with high-grade gliomas, the patients with brain metastases had lower FA values in the tumor parenchyma area, higher ADC values in the peritumoral edema area, and lower rCBV and rCBF values in the peritumoral edema area (all P<0.001).

conclusionThe measurement of the ADC, rCBV, and rCBF values in the peritumoral edema area and the FA values in the tumor parenchyma area using multimodal MRI can have essential clinical value in the differentiation between brain metastases and high-grade gliomas.

Indexed as

brain metastaseshigh-grade gliomasimaging featuresMultimodal magnetic resonance imaging

Identifiers

PMID34017534
PMCPMC8129411
OpenAlexW3162422912

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.