Evidence map›Paper›PMID 34017533›Full record

ArticleAmerican journal of translational research2021

Effects of two blood purification treatments combined with immunosuppressants on GM-CSF and CXCL16 levels in patients with lupus nephritis.

Juanjuan Shen, Limin Wang, Wei Jin, Weirong Fan, Xiaofeng Lu, Yuan Yang, Wenhan Bai, Wenqi Wu

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Juanjuan ShenDepartment of Nephrology, Tongxiang First People's Hospital Tongxiang, Zhejiang, China.
Limin WangDepartment of Nephrology, Tongxiang First People's Hospital Tongxiang, Zhejiang, China.
Wei JinDepartment of Nephrology, Tongxiang First People's Hospital Tongxiang, Zhejiang, China.
Weirong FanDepartment of Nephrology, Tongxiang First People's Hospital Tongxiang, Zhejiang, China.
Xiaofeng LuDepartment of Nephrology, Tongxiang First People's Hospital Tongxiang, Zhejiang, China.
Yuan YangDepartment of Nephrology, Tongxiang First People's Hospital Tongxiang, Zhejiang, China.
Wenhan BaiDepartment of Nephrology, Tongxiang First People's Hospital Tongxiang, Zhejiang, China.
Wenqi WuDepartment of Nephrology, Tongxiang First People's Hospital Tongxiang, Zhejiang, China.
Jiangxi Pingxiang People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to investigate the therapeutic effects of two different blood purification treatments combined with immunosuppressants on patients with lupus nephritis (LN) and their effects affecting granulocyte-macrophage colony-stimulating factor (GM-CSF) and CXC chemokine ligand-16 (CXCL16) levels.

methodsNinety patients with LN admitted to our hospital were enrolled and randomly assigned into groups A and B. Group A was treated with continuous veno-venous hemofiltration (CVVH) combined with conventional medical treatment (CMT, n = 40, including 23 females and 17 males), whereas group B was treated with intermittent hemodialysis combined with conventional medical treatment (n = 50, including 35 females and 15 males). Both groups received prednisone and cyclophosphamide.

resultsGM-CSF and CXCL16 levels in the two groups were significantly reduced after treatment (

conclusionCVVH combined with conventional medical treatment is more effective than intermittent hemodialysis combined with conventional medical treatment, and is easier to remove GM-CSF and CXCL16.

Indexed as

Blood purification treatmentCXCL16GM-CSFimmunosuppressantlupus nephritis

Identifiers

PMID34017533
PMCPMC8129358
OpenAlexW3161901875

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.