ArticleAmerican journal of translational research2021
The effect of intra-articular injection of antibacterial drugs in the clinical treatment of prosthetic joint infection in patients undergoing artificial hip replacement.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Effect of Rehabilitation Nursing under the Guidance of the Health Action Process Approach Model on Perioperative Nursing Effect of Artificial Hip Arthroplasty: Effect on Promoting Quality of Life and Postoperative Rehabilitation.Computational and mathematical methods in medicine · 2022Trial
- Changes in serum inflammatory factors after hip arthroplasty and analysis of risk factors for prosthesis loosening.American journal of translational research · 2024Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the clinical effect of intra-articular injection of antimicrobials in the treatment of prosthetic joint infection (PJI) in patients undergoing artificial hip replacement surgery and its impact on the quality of life.
methodsA retrospective analysis of the clinical data of 116 patients with PJI after artificial hip replacement in our hospital from June 2016 to June 2017 was performed, and they were randomly divided into a study group and a control group, with 58 in each group. The study group was treated with intra-articular injection of antibacterial drugs, and the control group was injected with sodium hyaluronate. The antibacterial effects of the two groups were compared.
resultsThe HHS scores of the two groups of patients after treatment increased (P < 0.001), and the increase of the study group was more relevant (P < 0.001). The IL-17 and IL-6 levels noticeably decreased (P < 0.001), and the decrease in the study group was more significant (P < 0.001). The total effective rate after 6 weeks of treatment in the study group was evidently higher compared with the control group (P < 0.05). The quality of life scores of the two groups of patients after treatment increased (P < 0.001), and the the study group was much better (P < 0.001). Lower incidence of adverse reactions was identified in the study group (P < 0.05).
conclusionIntra-articular injection of antimicrobials can effectively improve the hip joint function of patients, reduce inflammation, improve the quality of life, and the incidence of adverse reactions is relatively low. It has high clinical application value and is worthy of use and promotion.
Indexed as
Identifiers
34017529PMC8129305W3162532544What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.