Evidence map›Paper›PMID 34017466›Full record

ArticleAmerican journal of translational research2021

The value of inflammatory factors and red blood cell immune indices in predicting perinatal infection in hypertensive women after cesarean section.

Wenju Yang, Xiaocui Fan, Xia Du, Zhen Wang, Min Wang, Ningning Cao

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wenju YangObstetrics Department, Liaocheng Dongchangfu District Maternity and Child Health Hospital Liaocheng 252000, Shandong Province, China.
Xiaocui FanObstetrics Department, Liaocheng Dongchangfu District Maternity and Child Health Hospital Liaocheng 252000, Shandong Province, China.
Xia DuObstetrics Department, Liaocheng Dongchangfu District Maternity and Child Health Hospital Liaocheng 252000, Shandong Province, China.
Zhen WangObstetrics Department, Liaocheng Dongchangfu District Maternity and Child Health Hospital Liaocheng 252000, Shandong Province, China.
Min WangObstetrics Department, Liaocheng Dongchangfu District Maternity and Child Health Hospital Liaocheng 252000, Shandong Province, China.
Ningning CaoObstetrics Department, Liaocheng Dongchangfu District Maternity and Child Health Hospital Liaocheng 252000, Shandong Province, China.
Liaocheng People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was conducted to explore the predictive value of inflammatory factors and red blood cell (RBC) immune indices in perinatal infection of women with pregnancy-induced hypertension after cesarean section.

methodsEighty women with pregnancy-induced hypertension and perinatal infection after cesarean section were enrolled as the study group. Another 80 pregnant women with hypertension but without perinatal infection during cesarean section were included as the control group. The two groups were compared in terms of interleukin-1β (IL-1β), IL-6, IL-10, transformation growth factor-β (TGF-β), tumor necrosis factor-α (TNF-α), γ-interferon (IFN-γ), immune adhesion inhibitor (FEIR), immune adhesion promotion factor (FEER), and immune complex rosette (RBC-ICR) levels. The mothers in the study group were grouped according to the level of white blood cells, and the differences in related indicators of women in different inflammatory states were compared. Finally, the correlation between inflammatory factors and RBC-related immune indices was calculated. The differences in inflammatory factors and RBC-related immune indices were evaluated among different infection types. The ROC curve of IL-1β, IL-6, IL-10 and FEIR, FEER, RBC-ICR for infection prediction was plotted.

resultsThe study group showed significantly higher maternal levels of inflammatory factors and FEIR and lower FEER and RBC-ICR than the control group (

conclusionPrior to perinatal infection, the inflammatory factors and the RBC indices of women with hypertension and cesarean section are significantly altered. Monitoring these indicators can be used to evaluate maternal prognosis.

Indexed as

cesarean sectiongestational hypertensionInflammatory factorsperinatal infectionpredictive valueRBC indices

Identifiers

PMID34017466
PMCPMC8129257
OpenAlexW3163518179

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.