Evidence map›Paper›PMID 34017460›Full record

ArticleAmerican journal of translational research2021

The clinical significance of changes in cTnT, CRP and NT-proBNP levels in patients with heart failure.

Qingsong Wang, Yu An, Hong Wang, Na Zhang, Shuai Deng

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Vericiguat on C-reactive Protein Level and Prognosis in Patients with Hypertensive Heart Failure.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Trial
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qingsong WangDepartment of Cardiology, Affiliated Hospital of Chengde Medical College Chengde 067000, Hebei Province, China.
Yu AnDepartment of Cardiology, Affiliated Hospital of Chengde Medical College Chengde 067000, Hebei Province, China.
Hong WangDepartment of Cardiology, Affiliated Hospital of Chengde Medical College Chengde 067000, Hebei Province, China.
Na ZhangDepartment of Cardiology, Affiliated Hospital of Chengde Medical College Chengde 067000, Hebei Province, China.
Shuai DengEmergency Department, Affiliated Hospital of Chengde Medical College Chengde 067000, Hebei Province, China.
Affiliated Hospital of Chengde Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was designed to explore the clinical significance of changes in troponin T (cTnT), C-reactive protein (CRP) and amino-terminal pro-brain natriuretic peptide (NT-proBNP) levels in patients with heart failure (HF).

methodsA total of 193 patients with HF admitted to our hospital from October 2013 to June 2019 were enrolled as the study subjects (group A). Another 191 healthy controls were included as group B. Both groups were compared in terms of cTnT, CRP, NT-proBNP levels and left ventricular ejection fraction (LVEF), and the correlations between LVEF and cTnT, CRP, NT-proBNP were analyzed. The differences in cTnT, CRP, NT-proBNP were compared among patients with different cardiac function, different causes of HF, and between patients with and without cardiac events.

resultscTnT, CRP, and NT-proBNP levels in group A were higher than those in group B (

conclusioncTnT, CRP and NT-proBNP levels were elevated in patients with HF, which were negatively correlated with LVEF, and their levels increased with the improvement of cardiac function, independent of the cause of HF. The combination of these three indices is of great significance in the diagnosis and prognosis of HF.

Indexed as

amino-terminal brain natriuretic peptide precursorclinical significanceC-reactive proteinHeart failuretroponin T

Identifiers

PMID34017460
PMCPMC8129395
OpenAlexW3162221203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.