Evidence map›Paper›PMID 34017455›Full record

ArticleAmerican journal of translational research2021

Influence of Xuebijing injection combined with cefoperazone sodium and sulbactam sodium in treating hepatitis B-induced liver cirrhosis complicated by spontaneous bacterial peritonitis: TNF-α, IL-18, IL-6, and hepatic function.

Dong Qian, Ya'nan Zhang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dong QianThe Third Department of Hepatobiliary and Pancreatic Surgery, Tianjin Nankai Hospital Tianjin 300100, China.
Ya'nan ZhangThe Third Department of Hepatobiliary and Pancreatic Surgery, Tianjin Nankai Hospital Tianjin 300100, China.
Tianjin Third Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the influences of Xuebijing injection combined with cefoperazone sodium and sulbactam sodium (CSSS) in the treatment of hepatitis B-induced liver cirrhosis (HBLC) complicated by spontaneous bacterial peritonitis (SBP) with respect to tumor necrosis factor-α (TNF-α), interleukin-18 (IL-18), interleukin-6 (IL-6), and hepatic function.

methodsA total of 98 patients with HBLC complicated by SBP admitted to our hospital were selected and divided into the control group (CON, n=49) and the observation group (OBG, n=49) in accordance with the therapeutic methods. The clinical data of the patients were retrospectively analyzed. The CON was treated with CSSS, while the OBG was treated with Xuebijing injection combined with CSSS. The time of symptomatic improvement and changes of serum inflammatory factors and indices of intestinal mucosal barrier damage and hepatic function were compared between the two groups before and after treatment.

resultsThe time of symptomatic improvement in the OBG was shorter than that in the CON (

conclusionXuebijing injection combined with CSSS is conducive to improving the inflammatory responses of the body, intestinal tract barrier function, and hepatic function, showing satisfactory efficacy in the treatment of HBLC complicated by SBP.

Indexed as

cefoperazone sodium and sulbactam sodiumcombined therapyhepatic functionHepatitis Binflammatory factorliver cirrhosisspontaneous bacterial peritonitisXuebijing injection

Identifiers

PMID34017455
PMCPMC8129332
OpenAlexW3160909227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.