Evidence map›Paper›PMID 34017454›Full record

ArticleAmerican journal of translational research2021

Effects of bevacizumab combined with oxaliplatin intrathoracic injection on tumor markers and survival rate in patients with malignant pleural effusion of lung cancer.

Xiaoju Chen, Jiali Lu, Yien Yao, Zhongchen Huang, Ke Liu, Wenxin Jiang, Chaoqian Li

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. mSystems · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoju ChenDepartment of General Internal Medicine, Affiliated Tumor Hospital of Guangxi Medical University Nanning 530021, Guangxi, China.
Jiali LuDepartment of Respiratory Medicine, First Affiliated Hospital of Guangxi Medical University Nanning 530021, Guangxi, China.
Yien YaoDepartment of Respiratory Medicine, First Affiliated Hospital of Guangxi Medical University Nanning 530021, Guangxi, China.
Zhongchen HuangDepartment of Respiratory Medicine, First Affiliated Hospital of Guangxi Medical University Nanning 530021, Guangxi, China.
Ke LiuDepartment of Respiratory Medicine, First Affiliated Hospital of Guangxi Medical University Nanning 530021, Guangxi, China.
Wenxin JiangDepartment of General Internal Medicine, Affiliated Tumor Hospital of Guangxi Medical University Nanning 530021, Guangxi, China.
Chaoqian LiDepartment of Respiratory Medicine, First Affiliated Hospital of Guangxi Medical University Nanning 530021, Guangxi, China.
First Affiliated Hospital of GuangXi Medical University · CNGuangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aims to explore the therapeutic effects of bevacizumab combined with oxaliplatin on patients with malignant pleural effusion of lung cancer.

methodsA total of 109 patients with malignant pleural effusion of lung cancer admitted to our hospital from March 2015 to April 2017 were selected as research objects. Among them, 59 patients treated with bevacizumab combined with oxaliplatin intrathoracic injection were enrolled in the observation group, and another 50 patients treated with oxaliplatin intrathoracic injection were enrolled in the regular group. Clinical efficacy and safety of the two groups were compared, as well as the expression of vascular endothelial growth factor (VEGF), vascular endothelial growth factor receptor (VEGFR) and tumor markers before and after treatment. The two groups of patients were followed up for 3 years to compare their prognosis, survival and quality of life.

resultsThe cure rate of the observation group was higher than that of the regular group (

conclusionBevacizumab combined with oxaliplatin intrathoracic injection is effective in treating malignant pleural effusion of lung cancer.

Indexed as

Bevacizumab combined with oxaliplatinlung cancermalignant pleural effusionprognosis

Identifiers

PMID34017454
PMCPMC8129278
OpenAlexW3160807116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.