ArticleAmerican journal of translational research2021
Effects of Xinnaoning combined with trimetazidine on the levels of CK and its isoenzymes, AST, ALT and LDH in patients with myocardial ischemia.
Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Clinical changes of cardiac function from high altitude returning to plain.Scientific reports · 2025Article
- A new online dynamic nomogram based on the inflammation burden index to predict cardiac injury after antitumor therapy in lung cancer patients.Cardio-oncology (London, England) · 2025Article
- Dihydromyricetin Protects Against Hypoxia/Reoxygenation Injury in Cardiomyocytes by Activating miR-34a-Mediated Notch1 Pathway.Cardiovascular toxicology · 2025Article
- Exploring the effects ofFrontiers in pharmacology · 2025Article
- Ameliorative effect of mussel-derived ACE inhibitory peptides on spontaneous hypertension rats.European journal of nutrition · 2023Article
- A retrospect study based on real-world data to observe metabolic function in cancer patients using albumin-bound paclitaxel.Scientific reports · 2023Article
- Use of Anti-angiogenic Drugs Potentially Associated With an Increase on Serum AST, LDH, CK, and CK-MB Activities in Patients With Cancer: A Retrospective Study.Frontiers in cardiovascular medicine · 2021Article
- Correlation Between Neutrophil to Lymphocyte Ratio and Myocardial Injury in Population Exposed to High Altitude.Frontiers in cardiovascular medicine · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the effect of combin3e uw3 of Xinnaoning and trimetazidine on the levels of creatine kinase (CK) and its isoenzymes (CK-MB), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in patients with myocardial ischemia (MI).
methodsA total of 137 patients with MI admitted to our hospital were enrolled in our study. Among them, 68 cases in the control group (CG) were treated with trimetazidine and 69 cases in the study group (SG) were treated with Xinnaoning on the basis of the CG. The incidence of adverse events, serum CK, CK-MB, AST, ALT, LDH levels, episodes of angina, lipid levels [total cholesterol (TC), triacylglycerol (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C)], and quality of life (SF-36) scores were compared between the two groups.
resultsThe total effective rate was 88.41% in the SG, which was higher than 73.53% in the CG (
conclusionThe regimen of Xinnaoning and trimetazidine could significantly improve cardiac function and serum cardiac enzyme levels, reduce lipid levels, and improve the quality of life in patients with MI.
Indexed as
Identifiers
34017451PMC8129328W3160785669What OpenQuestion holds
Registered trials
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