Evidence map›Paper›PMID 34017368›Full record

ArticleAmerican journal of translational research2021

Tracheal, bronchus, and lung cancer burden and related risk factors in the United States and China.

Yujiao Deng, Ling Peng, Na Li, Zhen Zhai, Dong Xiang, Xianghua Ye, Jingjing Hu, Yi Zheng, Jia Yao, Shuqian Wang and 5 more

Abstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  16. Incidence and risk factors of suicide in patients with lung cancer: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yujiao DengDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Ling PengDepartment of Radiotherapy, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Na LiDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Zhen ZhaiDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Dong XiangCelilo Cancer Center, Oregon Health Science Center Affiliated Mid-Columbia Medical Center The Dalles, OR, USA.
Xianghua YeDepartment of Radiotherapy, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Jingjing HuDana-Farber Cancer Institute, Harvard Medical School Boston, MA, USA.
Yi ZhengDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Jia YaoDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Shuqian WangDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Bajin WeiDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Peng XuDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Dai ZhangDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.
Tianhui ChenDepartment of Cancer Prevention, Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)/Institute of Cancer and Basic Medicine, Chinese Academy of Sciences Hangzhou, China.
Zhijun DaiDepartment of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tracheal, bronchus, and lung (TBL) cancer is the most common malignant tumor worldwide. This study aims to grasp the characteristics of the TBL cancer burden in China and the United States (USA). Data included incidence, deaths, and disability-adjusted life years (DALYs) as well as their age-standardized rates (ASRs) among different gender, age and risk factors. Joinpoint Regression Model and Age-period-cohort (APC) analysis were used to evaluate the variation tendency and effect of the risk factors. China and USA bore almost half of the TBL cancer burden, especially for males. ASRs of TBL cancer increased in China, but decreased in USA. In China, three factors related to TBL cancer deaths and DALYs related were tobacco, air pollution, and diet low in fruits; in USA, these are tobacco, occupational carcinogens, and high fasting plasma glucose. The younger the population, the less impact of birth cohort on morbidity and mortality. According to APC analysis, age effect played a key role in morbidity and mortality of TBL cancer, and the risk increased with age. Period effect kept increasing over time, while cohort effect decreased with the time of birth. Tobacco was always the top risk factor of death and DALYs in both countries. The policy should be tilted towards air pollution and a diet low in fruits in China, as well as occupational carcinogens and high fasting plasma glucose in USA. Healthcare reform in both countries should focus on planning how its health system could effectively prevent and manage TBL cancer at low cost.

Indexed as

Age-period-cohort modelbronchusGBD studyjoinpoint regressionlung cancerrisk factorstracheal

Identifiers

PMID34017368
PMCPMC8129289

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.