Evidence map›Paper›PMID 34017343›Full record

Trial reportFrontiers in immunology2021

Antibodies Elicited by the

Francesca Micoli, Omar Rossi, Valentino Conti, Odile Launay, Antonella Silvia Sciré, Maria Grazia Aruta, Usman Nasir Nakakana, Elisa Marchetti, Rino Rappuoli, Allan Saul and 3 more

Open access · goldAbstract readClinical Trial, Phase IRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Human vaccines & immunotherapeutics · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Immunogenicity evaluation of altSonflex1-2-3Frontiers in immunology · 2025
    Article
  8. Article
  9. TestingPharmaceutics · 2024
    Article
  10. Article
  11. Review
  12. Oral immunization withmSphere · 2024
    Article
  13. Outer Membrane Vesicle Vaccine Platforms.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2024
    Review
  14. Article
  15. Age-dependent acquisition of IgG antibodies toFrontiers in immunology · 2024
    Article
  16. Article
  17. Review
  18. Article
  19. Toward aInternational journal of molecular sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Francesca MicoliGSK Vaccines Institute for Global Health, Siena, Italy.
Omar RossiGSK Vaccines Institute for Global Health, Siena, Italy.
Valentino ContiGSK Vaccines Institute for Global Health, Siena, Italy.
Odile LaunayFaculté de Médecine Paris Descartes, Université de Paris, Paris, France.
Antonella Silvia SciréGSK Vaccines Institute for Global Health, Siena, Italy.
Maria Grazia ArutaGSK Vaccines Institute for Global Health, Siena, Italy.
Usman Nasir NakakanaGSK Vaccines Institute for Global Health, Siena, Italy.
Elisa MarchettiGSK Vaccines Institute for Global Health, Siena, Italy.
Rino RappuoliGSK Vaccines Institute for Global Health, Siena, Italy.
Allan SaulGSK Vaccines Institute for Global Health, Siena, Italy.
Laura B MartinGSK Vaccines Institute for Global Health, Siena, Italy.
Francesca NecchiGSK Vaccines Institute for Global Health, Siena, Italy.
Audino PoddaGSK Vaccines Institute for Global Health, Siena, Italy.
GlaxoSmithKline (Italy) · ITToscana Life Sciences · ITHôpital Cochin · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, BacterialAntibody-Dependent Cell CytotoxicityBacterial VaccinesComplement System ProteinsDysentery, BacillaryFemaleHigh-Throughput Screening AssaysHumansImmunologic MemoryMaleO AntigensPlacebo EffectSerum Bactericidal Antibody AssayShigella sonneiVaccine PotencyAntibodies, BacterialBacterial VaccinesComplement System ProteinsO Antigens1790GAHBbooster responsedose escalationGMMAserum bactericidal activityShigella sonnei

Identifiers

PMID34017343
PMCPMC8129577
OpenAlexW3157588003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.