Evidence map›Paper›PMID 34017319›Full record

ArticleFrontiers in microbiology2021

LpxT-Dependent Phosphorylation of Lipid A in

Xudong Tian, Guillaume Manat, Elise Gasiorowski, Rodolphe Auger, Samia Hicham, Dominique Mengin-Lecreulx, Ivo Gomperts Boneca, Thierry Touzé

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Analysis of stress-induced small proteins inbioRxiv : the preprint server for biology · 2025
    Article
  4. The fatty acid synthesis geneMicrobiology spectrum · 2025
    Article
  5. ISmBio · 2024
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Xudong TianUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Guillaume ManatUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Elise GasiorowskiInstitut Pasteur, Unité Biologie et Génétique de la Paroi Bactérienne, Paris, France.
Rodolphe AugerUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Samia HichamInstitut Pasteur, Unité Biologie et Génétique de la Paroi Bactérienne, Paris, France.
Dominique Mengin-LecreulxUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Ivo Gomperts BonecaInstitut Pasteur, Unité Biologie et Génétique de la Paroi Bactérienne, Paris, France.
Thierry TouzéUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Centre National de la Recherche Scientifique · FRInstitut Pasteur · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRSorbonne Paris Cité · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cell surface of Gram-negative bacteria usually exhibits a net negative charge mostly conferred by lipopolysaccharides (LPS). This property sensitizes bacterial cells to cationic antimicrobial peptides, such as polymyxin B, by favoring their binding to the cell surface. Gram-negative bacteria can modify their surface to counteract these compounds such as the decoration of their LPS by positively charged groups. For example, in

Indexed as

antibiotic resistancebile acidlipid Alipopolysaccharidespolymyxin Btwo-component system

Identifiers

PMID34017319
PMCPMC8129183
OpenAlexW3159039085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.