Evidence map›Paper›PMID 34017174›Full record

ArticleTherapeutics and clinical risk management2021

Microvascular Changes in Macular Area After Phacoemulsification and Its Influencing Factors Assessed by Optical Coherence Tomography Angiography.

Jun Liu, Qiang Liu, Hua Yu, Ye Xia, Hui Zhang, Chao Geng, Lihong Dong

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. The effect of intraocular pressure during phacoemulsification in patients with either diabetic retinopathy or glaucoma; a randomized controlled feasibility trial.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jun LiuDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People's Republic of China.
Qiang LiuDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People's Republic of China.
Hua YuDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People's Republic of China.
Ye XiaDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People's Republic of China.
Hui ZhangDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People's Republic of China.
Chao GengDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People's Republic of China.
Lihong DongDepartment of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei, 238000, Anhui, People's Republic of China.
Chaohu Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate macular vascular changes and underlying influencing factors using optical coherence tomography angiography (OCTA) after phacoemulsification in patients with cataracts.

methodsPatients diagnosed with cataracts at the First Affiliated Hospital of Anhui Medical University from March to September 2019 were included. The macular retinal thickness, the microvascular density in the foveal, parafoveal, and perifoveal area, and the area of the foveal avascular zone (FAZ) were measured using OCTA at baseline, 1-week, 1-month, and 3-month post-operation.

resultsForty-seven cataract patients (58 eyes) were eligible for this study. Compared with baseline thickness, the foveal, parafoveal, and perifoveal thicknesses, particularly in the inner retina, significantly increased at 1- and 3-month post-operation (P<0.05). There was a nonsignificant difference in the microvascular density of the foveal and perifoveal areas at 1-week, 1-month, and 3-month post-operation (P>0.05). At 1-month post-operation, the deep vessel density at the perifovea significantly increased (P<0.05). The FAZ area significantly diminished at 1- and 3-month post-operation compared with the baseline data (P<0.05).

conclusionPhacoemulsification offers a satisfactory efficacy response, with an increased macular thickness, reduced FAZ area, and nonsignificant changes in the microvascular density at the perifovea after surgery.

Indexed as

cataractsmacular thicknessmicrovascular densityoptical coherence tomographyphacoemulsification

Identifiers

PMID34017174
PMCPMC8131067
OpenAlexW3163414068

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.