ReviewEvolutionary bioinformatics online2021
The Missing Piece: Recent Approaches Investigating the Antimicrobial Mode of Action of Essential Oils.
Review in Evolutionary bioinformatics online, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Essential Oil Blends or Their Component Blends as Antimicrobial Compounds of Polysaccharide Coatings on Metallic Biomaterials.Materials (Basel, Switzerland) · 2026Article
- GNPS Untargeted GC-MS Metabolomic Analysis of Essential Oils From Duguetia lanceolata and Evaluation of Antimicrobial Activity.Chemistry & biodiversity · 2026Article
- Article
- Essential Oils as Natural Defenders: Exploring Their Antioxidant and Antimicrobial Potential Against Multidrug-Resistant (MDR) Bacteria.International journal of microbiology · 2026Article
- Essential Oils as Antimicrobial Agents Against WHO Priority Bacterial Pathogens: A Strategic Review of In Vitro Clinical Efficacy, Innovations and Research Gaps.Antibiotics (Basel, Switzerland) · 2025Review
- The Natural Disinfectant Role of Essential Oils in Improving Radical Scavenging Activity and Total Phenolic Compounds in Fresh Vegetables.Antioxidants (Basel, Switzerland) · 2025Article
- Fully Green Particles Loaded with Essential Oils as Phytobiotics: A Review on Preparation and Application in Animal Feed.Antibiotics (Basel, Switzerland) · 2025Review
- Antimicrobial Action of Essential Oil ofAntibiotics (Basel, Switzerland) · 2025Article
- Effect of Temperature, Surface, and Medium Qualities on the Biofilm Formation ofFoods (Basel, Switzerland) · 2025Article
- Facing Foodborne Pathogen Biofilms with Green Antimicrobial Agents: One Health Approach.Molecules (Basel, Switzerland) · 2025Review
- The Influence of Basil and Cinnamon Essential Oils on Bioactive Sponge Composites of Collagen Reinforced with Hydroxyapatite.Materials (Basel, Switzerland) · 2025Article
- Synergistic antimicrobial interaction of plant essential oils and extracts against foodborne pathogens.Food science & nutrition · 2024Article
- Growth Performance and Disease Resistance againstAnimals : an open access journal from MDPI · 2023Article
- Tea Tree Essential Oil KillsBiomolecules · 2023Article
- Microbial Genomics: Innovative Targets and Mechanisms.Antibiotics (Basel, Switzerland) · 2023Review
- Anti- and Pro-Oxidant Properties of Essential Oils against Antimicrobial Resistance.Antioxidants (Basel, Switzerland) · 2022Review
- Chemical Composition, Biological Activities and In Silico Analysis of Essential Oils of Three EndemicMolecules (Basel, Switzerland) · 2022Article
- Machine Learning Analysis of Essential Oils from Cuban Plants: Potential Activity against Protozoa Parasites.Molecules (Basel, Switzerland) · 2022Article
- Progress in Alternative Strategies to Combat Antimicrobial Resistance: Focus on Antibiotics.Antibiotics (Basel, Switzerland) · 2022Review
- Metabolomics-Driven Exploration of the Antibacterial Activity and Mechanism of 2-Methoxycinnamaldehyde.Frontiers in microbiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotic resistance is a major global health issue that has seen alarming rates of increase in all parts of the world over the past two decades. The surge in antibiotic resistance has resulted in longer hospital stays, higher medical costs, and elevated mortality rates. Constant attempts have been made to discover newer and more effective antimicrobials to reduce the severity of antibiotic resistance. Plant secondary metabolites, such as essential oils, have been the major focus due to their complexity and bioactive nature. However, the underlying mechanism of their antimicrobial effect remains largely unknown. Understanding the antimicrobial mode of action of essential oils is crucial in developing potential strategies for the use of essential oils in a clinical setting. Recent advances in genomics and proteomics have enhanced our understanding of the antimicrobial mode of action of essential oils. We might well be at the dawn of completing a mystery on how essential oils carry out their antimicrobial activities. Therefore, an overview of essential oils with regard to their antimicrobial activities and mode of action is discussed in this review. Recent approaches used in identifying the antimicrobial mode of action of essential oils, specifically from the perspective of genomics and proteomics, are also synthesized. Based on the information gathered from this review, we offer recommendations for future strategies and prospects for the study of essential oils and their function as antimicrobials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.