ArticleScientific reports2021
Frailty transitions and cognitive function among South Korean older adults.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- The association between sedentary behavior and falls in older adults: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Impact of frailty, mild cognitive impairment and cognitive frailty on adverse health outcomes among community-dwelling older adults: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Gait asymmetry across frailty-status groups in older adults: clinical and biomechanical evidence from 3D gait analysis.Annals of medicine · 2026Article
- Late-stage interventional trials reporting sleep-related outcomes in older adults with Parkinson's disease: a ClinicalTrials.gov registry review.BMC geriatrics · 2026Review
- Article
- Association between malnutrition and cognitive decline in Chinese older adults: the mediating role of physical frailty.Frontiers in public health · 2026Article
- Association between frailty and cognitive function in hospitalized older adults: a moderated serial mediation analysis involving functional status, depression, and social support.Frontiers in public health · 2026Article
- Association of transitions in frailty with dementia risk: findings from two longitudinal cohort studies.Frontiers in medicine · 2026Article
- Association between frailty and cognitive function: a pooled analysis of three ageing cohorts.Translational psychiatry · 2025Article
- The cross-sectional relationship of physical frailty and cognitive impairment in older Poles: analysis of the PolSenior2 data.European geriatric medicine · 2025Article
- An individualized physical function improvement program for frailty elderly using goal attainment scaling (GAS) as evaluation method: protocol for a randomized controlled trial.BMC geriatrics · 2025Article
- Association of changes in frailty with mortality in the aged with hypertension.Scientific reports · 2025Article
- Factors Associated with Frailty Transitions Using the Kihon Checklist: A 6-Year Longitudinal Study Among Japanese Residents.Clinical interventions in aging · 2025Article
- A trajectory study of postoperative frailty and cognitive function in elderly spinal surgery patients: a cohort study in China.Frontiers in aging neuroscience · 2025Article
- The mediating role of individual evaluation, anxiety, and depression in the association between leisure activity and cognitive function among Chinese older adults.Scientific reports · 2024Article
- Sustained frailty remission and dementia risk in older adults: A longitudinal study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Trajectories of cognitive function and frailty in older adults in China: a longitudinal study.Frontiers in aging neuroscience · 2024Article
- Dual trajectories of social participation and frailty in Chinese older adults: a longitudinal study based on CLHLS from 2008 to 2018.Frontiers in public health · 2024Article
- Subjective Cognitive Decline and Frailty Trajectories and Influencing Factors in Japanese Community-Dwelling Older Adults: A Longitudinal Study.Journal of clinical medicine · 2023Article
- Frailty trajectory predicts subsequent cognitive decline: A 26-year population-based longitudinal cohort study.MedComm · 2023Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty is considered a multidimensional geriatric syndrome, manifested by the accumulation of age-associated deficits. The consequences of frailty transitions are still understudied. This study evaluated the influence of frailty transitions on cognitive function in the older adult population. We used data derived from the Korean Longitudinal Study of Aging (KLoSA) (2008-2018) on older adults aged ≥ 65 years. Frailty was assessed using a validated Korean frailty measure known as the frailty instrument (FI), and cognitive function was measured using the Korean version of the Mini-Mental State Examination (K-MMSE). Transitions in frailty and their relationship with cognitive function were investigated using lagged generalized estimating equations (GEE), t-tests, and ANOVA. Respondents who experienced frailty transitions (those with ameliorating frailty), those who developed frailty, and whose frailty remained constant, were more likely to have a lower cognitive function than those who were consistently non-frail. Older age, activities of daily living (ADL) disability, and instrumental ADL disability were more negatively associated with declining cognitive function, especially in the "frail → frail" group. Changes in all individual components of the frailty instrument were significantly associated with impaired cognitive function. The results suggest an association between frailty transitions and cognitive impairment. Over a 2-year span, the remaining frail individuals had the highest rate of cognitive decline in men, while the change from non-frail to frail state in women was significantly associated with the lowest cognitive function values. We recommend early interventions and prevention strategies in older adults to help ameliorate or slow down both frailty and cognitive function decline.
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