ArticleTranslational psychiatry2021
The costs of over-control in anorexia nervosa: evidence from fMRI and ecological momentary assessment.
Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- Annual Research Review: Neural mechanisms of eating disorders in youth - from current theory and findings to future directions.Journal of child psychology and psychiatry, and allied disciplines · 2026Review
- Illness Perceptions in Psychiatric Disorders: Assessing Differences and Associations With Symptom Severity.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- Evaluating the efficacy of radically open dialectical behavior therapy (RO-DBT) in patients with anorexia nervosa: study protocol for a randomized controlled clinical trial.BMC psychiatry · 2025Article
- Exaggerated frontoparietal control over cognitive effort-based decision-making in young women with anorexia nervosa.Molecular psychiatry · 2025Article
- Does Evidence Support an Emotion Regulation Model of Anorexia Nervosa? A Systematic Review of Over a Decade of Research.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2025Article
- The Willpower Paradox: Possible and Impossible Conceptions of Self-Control.Perspectives on psychological science : a journal of the Association for Psychological Science · 2023Article
- White matter microstructure in habit and reward circuits in anorexia nervosa: Insights from a neurite orientation dispersion and density imaging study.Acta psychiatrica Scandinavica · 2023Article
- Social Processing in Eating Disorders: Neuroimaging Paradigms and Research Domain Organizational Constructs.Current psychiatry reports · 2022Review
- Overcontrol in anorexia nervosa: Elevated prefrontal activity and amygdala connectivity in a working memory task with food distractors.International journal of clinical and health psychology : IJCHPArticle
- A longitudinal study on the change of eating disorder-specific and nonspecific habits during weight rehabilitation in anorexia nervosa.International journal of clinical and health psychology : IJCHPArticle
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
A growing body of evidence suggests that a high level of self-control may, despite its positive effects, influence cognitive processing in an unfavorable manner. However, the affective costs of self-control have only rarely been investigated. Anorexia nervosa (AN) is an eating disorder that is often characterized by excessive self-control. Here, we used fMRI to explore whether over-control in AN may have negative affective consequences. 36 predominantly adolescent female AN patients and 36 age-matched healthy controls (HC) viewed negative and neutral pictures during two separate fMRI sessions before and after 10 min of rest. We tested whether abnormally elevated neural activity during the initial presentation in a brain region broadly implicated in top-down control, the dorsolateral prefrontal cortex (dlPFC), could predict subsequent activation in limbic areas relevant to bottom-up affective processing. Using ecological momentary assessment (EMA), we also tested for associations between the aforementioned neuroimaging markers and negative affective states in the two weeks following the experiment. fMRI data revealed that higher initial activation of the dlPFC in AN predicted increased amygdala reactivity during the second fMRI session, which in turn was related to increased self-reported tension during two weeks following the scan. These data suggest that over-control in AN patients may come at a cost including negative affective states on a short (minutes) as well as a longer time scale (days). This mechanism may significantly contribute to the persistence of AN.
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