Evidence map›Paper›PMID 34016899›Full record

ArticlePancreas

Acute and Severe Acute Pancreatitis and the Effect of Cannabis in States Before and After Legalization Compared With States Without Legalized Cannabis.

Luis F Lara, Laura Nemer, Alice Hinton, Gokulakrishnan Balasubramanian, Darwin L Conwell, Somashekar Krishna

Abstract readComparative Study
In one paragraph

Article in Pancreas. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luis F LaraFrom the Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center.
Laura NemerFrom the Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center.
Alice HintonDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH.
Gokulakrishnan BalasubramanianFrom the Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center.
Darwin L ConwellFrom the Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center.
Somashekar KrishnaFrom the Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center.

Funding

Advancing Treatment for Pancreatitis: A Prospective Observational Study of TPIATR01DK109124 · NIDDK · UNIVERSITY OF MINNESOTA · PI BELLIN, MELENA D. · 2016 to 2021
$4.0M
NIDDK NIH HHS R01 DK109124
6 · The paper itself

Abstract

objectivesCannabis legalization has increased its use. The incidence of acute pancreatitis (AP) and severe acute pancreatitis (SAP) has also increased. In this study, data on pancreatitis were obtained from 2 states before and after cannabis legalization and compared with 2 states without legalized cannabis.

methodsData were extracted from State Inpatient Databases from the states of Colorado and Washington before recreational cannabis legalization (2011) and after legalization (2015). Arizona and Florida were used as the nonlegalized cannabis states. Multivariable logistic regression models were fit for AP and SAP to determine a trend difference between legalized and nonlegalized cannabis states.

resultsCannabis use, AP, and SAP increased in all states. The increase in AP and SAP was not significantly different between the states that legalized cannabis use and those that did not. Legalized cannabis states had lower charges for AP and SAP and shorter length of hospitalizations.

conclusionsThe trend of AP and SAP increased during the study period, but this was not correlated to cannabis use. Cannabis users had lower hospitalization costs and hospital stay. The effects of other confounders such as cannabis dose and delivery methods, alcohol, tobacco, and others need to be studied further as use increases.

Indexed as

Recreational Drug UseAdolescentAdultAgedCannabisDatabases, FactualFemaleGovernment RegulationHospital CostsHumansIncidenceLegislation, DrugLength of StayMaleMarijuana SmokingMiddle Aged

Identifiers

PMID34016899
PMCPMC8192470

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.