ArticleScience (New York, N.Y.)2021
A brain-computer interface that evokes tactile sensations improves robotic arm control.
Article in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 233 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
233 citing papers in PubMed, 2 syntheses or guidelines pooled it, 548 citations in OpenAlex.
- Association between lesion location and sensorimotor rhythms in stroke - a systematic review with narrative synthesis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Pooled it
- Challenges and opportunities in vascularized composite allotransplantation of joints: a systematic literature review.Frontiers in immunology · 2023Pooled it
- Long-term safety and efficacy of intracortical microstimulation in humans.Science translational medicine · 2026Trial
- Biomimetic stimulation patterns drive natural artificial touch percepts using intracortical microstimulation in humans.Journal of neural engineering · 2025Trial
- How different immersive environments affect intracortical brain computer interfaces.Journal of neural engineering · 2025Trial
- Interim Safety Profile From the Feasibility Study of the BrainGate Neural Interface System.Neurology · 2023Trial
- Soft Mechanical Inductive Sensors: Principles, Design, and Applications.Micromachines · 2026Review
- Article
- Cross-region neural signal reconstruction to lift electrode placement constraints in SSVEP brain-computer interfaces.npj biomedical innovations · 2026Article
- Advancing data protections for implantable brain-computer interfaces.Communications medicine · 2026Review
- Bypass neural interfaces for paralysis: clinical translation, challenges and future directions.Journal of neuroengineering and rehabilitation · 2026Review
- Sensory-guided human-machine joint learning accelerates the acquisition of motor imagery brain computer interface control.Nature communications · 2026Article
- Active devices and systems for closed-loop neuromodulation.Microsystems & nanoengineering · 2026Review
- Electrophysiological Recording With Activated Iridium Oxide: Effective Electrode Area, Not Total Impedance, Determines Performance.The European journal of neuroscience · 2026Article
- A neuroprosthesis for restoring hand movement and sensation in a person with complete tetraplegia.Nature medicine · 2026Article
- Neural population dynamics of direct electrical stimulation of neocortex.Cell reports · 2026Article
- Adaptive Neural Reorganization Enables Real-Time Finger-Level Robotic Control in BCI-Naïve Stroke Survivors.bioRxiv : the preprint server for biology · 2026Article
- Laminar organization of cellular microcircuits modulating human interictal epileptiform discharges.Nature neuroscience · 2026Article
- Brain-Computer Interfaces: The Dawn of a New Era in Disease Treatment.Exploration (Beijing, China) · 2026Review
- Advances in neuroprostheses: interfaces, materials, and applications.Nano convergence · 2026Review
173 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
Prosthetic arms controlled by a brain-computer interface can enable people with tetraplegia to perform functional movements. However, vision provides limited feedback because information about grasping objects is best relayed through tactile feedback. We supplemented vision with tactile percepts evoked using a bidirectional brain-computer interface that records neural activity from the motor cortex and generates tactile sensations through intracortical microstimulation of the somatosensory cortex. This enabled a person with tetraplegia to substantially improve performance with a robotic limb; trial times on a clinical upper-limb assessment were reduced by half, from a median time of 20.9 to 10.2 seconds. Faster times were primarily due to less time spent attempting to grasp objects, revealing that mimicking known biological control principles results in task performance that is closer to able-bodied human abilities.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.