Evidence map›Paper›PMID 34016750›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

A stress-responsive miRNA regulates BMP signaling to maintain tissue homeostasis.

Sromana Mukherjee, Nuria Paricio, Nicholas S Sokol

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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  13. A stress-responsive miRNA regulates BMP signaling to maintain tissue homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sromana MukherjeeDepartment of Biology, Indiana University, Bloomington, IN 47405.ORCID 0000-0003-4290-9258
Nuria ParicioDepartamento de Genética, Facultad de Ciencies Biológicas and Estructura de Recerca Interdisciplinar en Biotecnologia i Biomedicina, University of Valencia, 46100 Burjasot, Spain.ORCID 0000-0001-7193-2532
Nicholas S SokolDepartment of Biology, Indiana University, Bloomington, IN 47405; nsokol@indiana.edu.ORCID 0000-0002-2768-4102
Indiana University Bloomington · USUniversitat de València · ES

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Post-transcriptional Control of Adaptive Tissue GrowthR01GM124220 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CALVI, BRIAN R · 2017 to 2020
$1.3M
Acquisition of a DeltaVision OMX-SR Imaging SystemS10OD024988 · OD · INDIANA UNIVERSITY INDIANAPOLIS · PI WALCZAK, CLAIRE E · 2018 to 2018
$600k
NIGMS NIH HHS R01 GM124220NIH HHS P40 OD018537NIH HHS S10 OD024988
6 · The paper itself

Abstract

Adult organisms must sense and adapt to environmental fluctuations. In high-turnover tissues such as the intestine, these adaptive responses require rapid changes in gene expression that, in turn, likely involve posttranscriptional gene control. However, intestinal-tissue-specific microRNA (miRNA)-mediated regulatory pathways remain unexplored. Here, we report the role of an intestinal-specific miRNA,

Indexed as

AnimalsBleomycinBone Morphogenetic ProteinsCell CountDrosophila melanogasterDrosophila ProteinsEnterocytesGene Expression RegulationGenes, ReporterGreen Fluorescent ProteinsHomeostasisMicroRNAsRegenerationSignal TransductionStem CellsTranscription FactorsBleomycinBone Morphogenetic ProteinsCbt protein, DrosophilaDrosophila ProteinsGreen Fluorescent ProteinsMicroRNAsMIRN958 microRNA, humanTranscription FactorsBMP signalingDrosophilaintestinemicroRNAmidgut

Identifiers

PMID34016750
PMCPMC8166057
OpenAlexW3160140252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.