Evidence map›Paper›PMID 34016711›Full record

ArticlemBio2021

Toward a Phage Cocktail for Tuberculosis: Susceptibility and Tuberculocidal Action of Mycobacteriophages against Diverse Mycobacterium tuberculosis Strains.

Carlos A Guerrero-Bustamante, Rebekah M Dedrick, Rebecca A Garlena, Daniel A Russell, Graham F Hatfull

Abstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Activity of a three-phage combination againstbioRxiv : the preprint server for biology · 2026
    Article
  7. Microbiology (Reading, England) · 2026
    Article
  8. Article
  9. bioRxiv : the preprint server for biology · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Genome synthesis, assembly, and rebooting of therapeutically useful high G+C% mycobacteriophages.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. All the world's a phage.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Article
  20. Review

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlos A Guerrero-BustamanteDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-7256-5188
Rebekah M DedrickDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-3666-711X
Rebecca A GarlenaDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Daniel A RussellDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-6894-2748
Graham F HatfullDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA gfh@pitt.edu.ORCID 0000-0002-6705-6821

Funding

Bacteriophage diversity, dynamics, function, and exploitationR35GM131729 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Graham F. Hatfull · 2019 to 2026
$3.6M
Phage resistance in Mycobacterium tuberculosisR21AI156791 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HATFULL, GRAHAM F. · 2021 to 2022
$396k
Howard Hughes Medical Institute GT12053NIAID NIH HHS R21 AI156791NIGMS NIH HHS R35 GM131729
6 · The paper itself

Abstract

The global health burden of human tuberculosis (TB) and the widespread antibiotic resistance of its causative agent

Indexed as

Phage TherapyAntitubercular AgentsHumansMycobacteriophagesMycobacterium smegmatisMycobacterium tuberculosisTuberculosis, Multidrug-ResistantAntitubercular Agentsbacteriophagesbacteriophage therapyMycobacterium tuberculosistuberculosis

Identifiers

PMID34016711
PMCPMC8263002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.