Evidence map›Paper›PMID 34016691›Full record

ArticleGenes & development2021

Natural antisense transcript of

Rebecca A Mosig, Allison N Castaneda, Jacob C Deslauriers, Landon P Frazier, Kevin L He, Naseem Maghzian, Aarati Pokharel, Camille T Schrier, Lily Zhu, Nobuya Koike and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. The sleep-wake history contributes to rhythmic BMAL1 chromatin binding in the cerebral cortex but not in the liver.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Article
  6. Coordination of rhythmic RNA synthesis and degradation orchestrates 24- and 12-h RNA expression patterns in mouse fibroblasts.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Circadian ribosome profiling reveals a role for theProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Rebecca A MosigDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.ORCID 0000-0003-4657-0052
Allison N CastanedaDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.ORCID 0000-0003-3603-2525
Jacob C DeslauriersDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.ORCID 0000-0002-6726-1462
Landon P FrazierDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.
Kevin L HeDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.ORCID 0000-0001-5778-043X
Naseem MaghzianDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.
Aarati PokharelDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.
Camille T SchrierDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.
Lily ZhuDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.
Nobuya KoikeDepartment of Physiology and Systems Bioscience, Kyoto Prefectural University of Medicine, Kyoto 062-8566, Japan.
John J TysonDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.ORCID 0000-0001-7560-6013
Carla B GreenDepartment of Neuroscience, The University of Texas Southwestern Medical Center, Dallas Texas 75390, USA.ORCID 0000-0002-3947-5156
Joseph S TakahashiDepartment of Neuroscience, The University of Texas Southwestern Medical Center, Dallas Texas 75390, USA.ORCID 0000-0003-0384-8878
Shihoko KojimaDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA.ORCID 0000-0001-9579-7830
Virginia Tech · USHoward Hughes Medical Institute · USKyoto Prefectural University of Medicine · JPThe University of Texas Southwestern Medical Center · US

Funding

Molecular mechanisms of mammalian circadian clock function - Renewal - 1R35GM127122 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Carla B. Green · 2018 to 2026
$6.0M
Functional analysis of a non-coding RNA in the mammalian circadian clock systemR01GM126223 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI KOJIMA, SHIHOKO · 2018 to 2022
$1.7M
NIGMS NIH HHS R01 GM126223NIGMS NIH HHS R35 GM127122
6 · The paper itself

Abstract

In mammals, a set of core clock genes form transcription-translation feedback loops to generate circadian oscillations. We and others recently identified a novel transcript at the

Indexed as

AnimalsCircadian ClocksFeedback, PhysiologicalGene Knockdown TechniquesMicePeriod Circadian ProteinsRNA, AntisensePer2 protein, mousePeriod Circadian ProteinsRNA, Antisenseamplitudeantisense transcriptcircadianlong noncoding RNAPeriod2

Identifiers

PMID34016691
PMCPMC8168560
OpenAlexW3162192318

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.