Evidence map›Paper›PMID 34016656›Full record

ArticlePediatrics2021

Comparing Pediatric Gastroenteritis Emergency Department Care in Canada and the United States.

Stephen B Freedman, Cindy G Roskind, Suzanne Schuh, John M VanBuren, Jesse G Norris, Phillip I Tarr, Katrina Hurley, Adam C Levine, Alexander Rogers, Seema Bhatt and 10 more

Abstract readComparative Study
In one paragraph

Article in Pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Observational
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Stephen B FreedmanSections of Pediatric Emergency Medicine and Gastroenterology, Departments of Pediatrics and Emergency Medicine, Alberta Children's Hospital and Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada; stephen.freedman@ahs.ca.
Cindy G RoskindDepartment of Emergency Medicine, Medical Center, Columbia University, New York, New York.
Suzanne SchuhDivision of Pediatric Emergency Medicine, Department of Pediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario.
John M VanBurenDepartment of Pediatrics, School of Medicine, University of Utah, Salt Lake City, Utah.
Jesse G NorrisDepartment of Pediatrics, School of Medicine, University of Utah, Salt Lake City, Utah.
Phillip I TarrDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, School of Medicine, Washington University in St Louis, St Louis, Missouri.
Katrina HurleyDepartment of Emergency Medicine, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada.
Adam C LevineDepartment of Emergency Medicine, Hasbro Children's Hospital, Rhode Island Hospital and Brown University, Providence, Rhode Island.
Alexander RogersDepartments of Emergency Medicine and Pediatrics, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.
Seema BhattDivision of Emergency Medicine, Department of Pediatrics, College of Medicine, University of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Serge GouinDepartment of Pediatrics, Faculty of Medicine, Université de Montréal, Montréal, Quebec, Canada.
Prashant MahajanDepartments of Emergency Medicine and Pediatrics, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.
Cheryl VanceDepartments of Emergency Medicine and Pediatrics, School of Medicine, University of California, Davis, Sacramento, California.
Elizabeth C PowellDepartment of Emergency Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago and Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Ken J FarionDivision of Emergency Medicine, Department of Pediatrics, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
Robert SapienDepartment of Emergency Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Karen O'ConnellDepartments of Pediatrics and Emergency Medicine, School of Medicine and Health Sciences, George Washington University and Children's National Hospital, Washington, DC; and.
Naveen PoonaiDepartments of Paediatrics, Internal Medicine, and Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, London, Ontario, Canada.
David Schnadower
Pediatric Emergency Research Canada and Pediatric Emergency Care Applied Research Networks

Funding

Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Nicholas O. Davidson · 2000 to 2026
$30.8M
Impact of Emergency Department Probiotic Treatment of Pediatric GastroenteritisR01HD071915 · NICHD · WASHINGTON UNIVERSITY · PI FREEDMAN, STEPHEN BRADLEY, SCHNADOWER, DAVID · 2014 to 2018
$3.6M
CIHR 286384CIHR 325412NICHD NIH HHS R01 HD071915NIDDK NIH HHS P30 DK052574
6 · The paper itself

Abstract

backgroundBetween-country variation in health care resource use and its impact on outcomes in acute care settings have been challenging to disentangle from illness severity by using administrative data.

methodsWe conducted a preplanned analysis employing patient-level emergency department (ED) data from children enrolled in 2 previously conducted clinical trials. Participants aged 3 to <48 months with <72 hours of gastroenteritis were recruited in pediatric EDs in the United States (

resultsIn adjusted analysis, unscheduled revisits within 7 days did not differ (adjusted odds ratio [aOR]: 0.72; 95% confidence interval (CI): 0.50 to 1.02). At the index ED visit, although participants in Canada were assessed as being more dehydrated, intravenous fluids were administered more frequently in the United States (aOR: 4.6; 95% CI: 2.9 to 7.1). Intravenous fluid administration rates did not differ after enrollment (aOR: 1.4; 95% CI: 0.7 to 2.8; US cohort with Canadian as referent). Overall, intravenous rehydration was higher in the United States (aOR: 3.8; 95% CI: 2.5 to 5.7). Although hospitalization rates during the 7 days after enrollment (aOR: 1.1; 95% CI: 0.4 to 2.6) did not differ, hospitalization at the index visit was more common in the United States (3.9% vs 2.3%; aOR: 3.2; 95% CI: 1.6 to 6.8).

conclusionsAmong children with gastroenteritis and similar disease severity, revisit rates were similar in our 2 study cohorts, despite lower rates of intravenous rehydration and hospitalization in Canadian-based EDs.

Indexed as

Emergency Service, HospitalCanadaChild, PreschoolFemaleGastroenteritisHospitalizationHumansInfantMaleUnited States

Identifiers

PMID34016656
PMCPMC8785749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.