ReviewJournal of pediatric urology2021
Modern management of and update on prune belly syndrome.
Review in Journal of pediatric urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06928974 (Functional Abdominal Wall Reconstruction in Patients With Prune Belly Syndrome), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Functional Abdominal Wall Reconstruction in Patients With Prune Belly Syndrome
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Survival of children with rare structural congenital anomalies: a multi-registry cohort study.Orphanet journal of rare diseases · 2022Pooled it
- Tc-99m Renal Scintigraphy in Complex Congenital Systemic Syndromes Associated with Congenital Anomalies of the Kidney and Urinary Tract: A Retrospective Single-Center Study.World journal of nuclear medicine · 2026Article
- Vaginal delivery in a woman with prune belly syndrome: a case report.AJOG global reports · 2026Article
- A case of prune belly syndrome with patent urachus: Pediatric surgical aspects of a rare case report.Radiology case reports · 2026Article
- Laparoscopic nephroureterectomy in Prune Belly Syndrome: a case report.International journal of surgery case reports · 2026Article
- A Case Report of a Syndromic Triad of Persistent Urogenital Sinus, Herlyn-Werner-Wunderlich Syndrome, and Prune Belly Syndrome in a Neonate.European journal of pediatric surgery reports · 2026Article
- Diagnostic and management challenges of prune belly syndrome in a low-income country: a neonatal case report.Journal of surgical case reports · 2025Article
- Case Report: A rare case of prune belly syndrome with intraperitoneal cryptorchidism.Frontiers in pediatrics · 2025Article
- Anatomic and Functional Reconstruction of the Abdominal Wall in Prune Belly Syndrome: A Case Report.Cureus · 2024Article
- Prune belly syndrome in a neonate with severe bilateral hydronephrosis: A rare case report from Somalia.International journal of surgery case reports · 2024Article
- Kidney function and transplants in prune belly syndrome: a scoping review.Pediatric nephrology (Berlin, Germany) · 2024Article
- PIEZO1 loss-of-function compound heterozygous mutations in the rare congenital human disorder Prune Belly Syndrome.Nature communications · 2024Article
- The challenging diagnosis and management of the prune belly syndrome: A case report.SAGE open medical case reports · 2024Article
- Prune Belly Syndrome in a Female Newborn following In Vitro Fertilization-Induced Pregnancy: A Case Report and Literature Review.Case reports in urology · 2023Article
- A case of prune belly syndrome: Experience from a regional hospital in Togo.International journal of surgery case reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Prune belly syndrome (PBS) is characterized by the triad of abdominal flaccidity, a variable degree of urinary tract involvement and cryptorchidism. Most cases of PBS are sporadic and have a normal karyotype, with 95% patients being male. In the last decade, mutations in known genes that regulate embryonic genitourinary myogenesis have been identified and with increasing knowledge of these critical genes involved in bladder maldevelopment, advances can be made in genetic counseling. A multidisciplinary approach is necessary and individualization of care is recommended according to phenotypic severity. Some patients require abdominal and urinary tract reconstruction while others require as little as bilateral orchiopexies. Major treatment objectives are: preservation of renal function and upper urinary tract; polyuria management; adequate bladder emptying; improvement of corporal image and quality of life; preservation of fertility and adequate sexual function. Long-term surveillance of the urinary tract is essential up to adulthood, because functional dynamics can change over time.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.