Evidence map›Paper›PMID 34016285›Full record

ReviewInfectious disease clinics of North America2021

Mucormycosis.

Julie M Steinbrink, Marisa H Miceli

Abstract readReview
In one paragraph

Review in Infectious disease clinics of North America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Ultrasonographic and Radiographic Features of Mucormycosis Causing Generalized Lymphadenopathy and Cranioventral Pulmonary Masses in an Immunocompetent Cat.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026
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  7. Epidemiological profile and clinical outcomes of patients with mucormycosis: the multicenter retromucor study from Türkiye (2004-2024).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  8. Invasive transmural fungal infection as a rare cause of thoracic aortic occlusion.Journal of vascular surgery cases and innovative techniques · 2026
    Article
  9. Review
  10. Inflammatory indices as early predictors of mortality in mucormycosis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Julie M SteinbrinkDivision of Infectious Diseases, Department of Internal Medicine, Duke University Medical Center, Hanes House, Duke University Medical Center, 315 Trent Drive, Durham, NC 27710, USA.
Marisa H MiceliDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan Health System, F4005 UH-South- SPC 5226, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address: mmiceli@med.umich.edu.

Funding

Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTGT32AI100851 · NIAID · DUKE UNIVERSITY · PI ALEXANDER, BARBARA D · 2013 to 2022
$1.8M
NIAID NIH HHS T32 AI100851
6 · The paper itself

Abstract

Mucormycosis is a rare but aggressive fungal disease that mainly affects patients with poorly controlled diabetes mellitus and those who are severely immunocompromised, including patients with hematological malignancies and solid organ transplant recipients. Early recognition of infection is critical for treatment success, followed by prompt initiation of antifungal therapy with lipid formulation amphotericin B. Posaconazole and isavuconazole should be used for stepdown and salvage therapy. Surgical debridement is key for tissue diagnosis and treatment and should be pursued urgently whenever possible. In addition to surgery and antifungal therapy, reverting the underlying risk factor for infection is important for treatment response.

Indexed as

Immunocompromised HostAntifungal AgentsDiabetes Mellitus, Type 2HumansMucoralesMucormycosisAntifungal AgentsDiabetes mellitusImmunocompromised hostMucoralesMucormycosis

Identifiers

PMID34016285
PMCPMC10110349

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.