Evidence map›Paper›PMID 34016116›Full record

ArticleBMC medical informatics and decision making2021

Development and user-testing of a brief decision aid for aspirin as a preventive approach alongside colorectal cancer screening.

Lenira Semedo, Kate J Lifford, Adrian Edwards, Kathy Seddon, Kate Brain, Stephanie Smits, Sunil Dolwani

Open access · goldAbstract read
In one paragraph

Article in BMC medical informatics and decision making, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Should I Take Aspirin? (SITA): randomised controlled trial of a decision aid for cancer chemoprevention.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lenira SemedoDivision of Population Medicine, Cardiff University, Cardiff, UK.
Kate J LiffordDivision of Population Medicine, Cardiff University, Cardiff, UK.
Adrian EdwardsDivision of Population Medicine, Cardiff University, Cardiff, UK.
Kathy SeddonDivision of Population Medicine, Cardiff University, Cardiff, UK.
Kate BrainDivision of Population Medicine, Cardiff University, Cardiff, UK.
Stephanie SmitsDivision of Population Medicine, Cardiff University, Cardiff, UK.
Sunil DolwaniDivision of Population Medicine, Cardiff University, Cardiff, UK. DolwaniS@cardiff.ac.uk.ORCID 0000-0002-3113-5472
Cardiff University · GBUniversity Hospital Llandough · GB

Funding

Tenovus [TIG2018-14].
6 · The paper itself

Abstract

backgroundSeveral epidemiological and cohort studies suggest that regular low-dose aspirin use independently reduces the long-term incidence and risk of colorectal cancer deaths by approximately 20%. However, there are also risks to aspirin use, mainly gastrointestinal bleeding and haemorrhagic stroke. Making informed decisions depends on the ability to understand and weigh up benefits and risks of available options. A decision aid to support people to consider aspirin therapy alongside participation in the NHS bowel cancer screening programme may have an additional impact on colorectal cancer prevention. This study aims to develop and user-test a brief decision aid about aspirin to enable informed decision-making for colorectal screening-eligible members of the public.

methodsWe undertook a qualitative study to develop an aspirin decision aid leaflet to support bowel screening responders in deciding whether to take aspirin to reduce their risk of colorectal cancer. The iterative development process involved two focus groups with public members aged 60-74 years (n = 14) and interviews with clinicians (n = 10). Interviews (n = 11) were used to evaluate its utility for decision-making. Analysis was conducted using a framework approach.

resultsOverall, participants found the decision aid acceptable and useful to facilitate decision-making. They expressed a need for individualised risk information, more detail about the potential risks of aspirin, and preferred risk information presented in pictograms when offered different options. Implementation pathways were discussed, including the possibility of involving different clinicians in the process such as GPs and/or community pharmacists. A range of potentially effective timepoints for sending out the decision aid were identified.

conclusionAn acceptable and usable decision aid was developed to support decisions about aspirin use to prevent colorectal cancer.

Indexed as

AspirinColorectal NeoplasmsDecision MakingDecision Support TechniquesEarly Detection of CancerHumansMass ScreeningAspirinAspirinBowel screeningCancer preventionColorectal cancerDecision-making

Identifiers

PMID34016116
PMCPMC8139147
OpenAlexW3163392062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.