Evidence map›Paper›PMID 34015860›Full record

SynthesisCA: a cancer journal for clinicians2021

Racial and socioeconomic disparities in lung cancer screening in the United States: A systematic review.

Ernesto Sosa, Gail D'Souza, Aamna Akhtar, Melissa Sur, Kyra Love, Jeanette Duffels, Dan J Raz, Jae Y Kim, Virginia Sun, Loretta Erhunmwunsee

Abstract readSystematic Review
In one paragraph

Synthesis in CA: a cancer journal for clinicians, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  3. Lung Cancer Screening Participation Among Indigenous Peoples Worldwide: A Systematic Review of Challenges and Opportunities.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2025
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ernesto SosaDepartment of Populations Sciences, City of Hope National Medical Center, Duarte, California.ORCID 0000-0002-2465-8988
Gail D'SouzaDepartment of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California.
Aamna AkhtarDepartment of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California.
Melissa SurDepartment of Populations Sciences, City of Hope National Medical Center, Duarte, California.
Kyra LoveDivision of Library Services, City of Hope National Medical Center, Duarte, California.
Jeanette DuffelsDivision of Library Services, City of Hope National Medical Center, Duarte, California.
Dan J RazDepartment of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California.
Jae Y KimDepartment of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California.
Virginia SunDepartment of Populations Sciences, City of Hope National Medical Center, Duarte, California.
Loretta ErhunmwunseeDepartment of Populations Sciences, City of Hope National Medical Center, Duarte, California.

Funding

Oncology Research Career Development ProgramK12CA001727 · NCI · CITY OF HOPE NATIONAL MEDICAL CENTER · PI MORTIMER, JOANNE E. · 1992 to 2024
$14.6M
AstraZeneca PharmaceuticalNCI NIH HHS K12 CA001727
6 · The paper itself

Abstract

Nonsmall cell lung cancer (NSCLC) is the leading cause of cancer deaths. Lung cancer screening (LCS) reduces NSCLC mortality; however, a lack of diversity in LCS studies may limit the generalizability of the results to marginalized groups who face higher risk for and worse outcomes from NSCLC. Identifying sources of inequity in the LCS pipeline is essential to reduce disparities in NSCLC outcomes. The authors searched 3 major databases for studies published from January 1, 2010 to February 27, 2020 that met the following criteria: 1) included screenees between ages 45 and 80 years who were current or former smokers, 2) written in English, 3) conducted in the United States, and 4) discussed socioeconomic and race-based LCS outcomes. Eligible studies were assessed for risk of bias. Of 3721 studies screened, 21 were eligible. Eligible studies were evaluated, and their findings were categorized into 3 themes related to LCS disparities faced by Black and socioeconomically disadvantaged individuals: 1) eligibility; 2) utilization, perception, and utility; and 3) postscreening behavior and care. Disparities in LCS exist along racial and socioeconomic lines. There are several steps along the LCS pipeline in which Black and socioeconomically disadvantaged individuals miss the potential benefits of LCS, resulting in increased mortality. This study identified potential sources of inequity that require further investigation. The authors recommend the implementation of prospective trials that evaluate eligibility criteria for underserved groups and the creation of interventions focused on improving utilization and follow-up care to decrease LCS disparities.

Indexed as

Early Detection of CancerHealthcare DisparitiesCarcinoma, Non-Small-Cell LungHumansLung NeoplasmsRace FactorsSocioeconomic FactorsUnited Statesdisparitieslung cancerlung cancer screeningracial minoritiessocioeconomic status

Identifiers

PMID34015860
PMCPMC8266751

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.