Evidence map›Paper›PMID 34015838›Full record

ArticleAmerican journal of perinatology2023

Deleterious and Protective Psychosocial and Stress-Related Factors Predict Risk of Spontaneous Preterm Birth.

Martin Becker, Jonathan A Mayo, Nisha K Phogat, Cecele C Quaintance, Ana Laborde, Lucy King, Ian H Gotlib, Brice Gaudilliere, Martin S Angst, Gary M Shaw and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of perinatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  9. Validation of the Assessment of Parent and Child Adversity (APCA) in Mothers and Young Children.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Martin Becker *Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California.
Jonathan A Mayo *Department of Pediatrics, Stanford University School of Medicine, Stanford, California.
Nisha K PhogatDepartment of Psychiatry and Behavioral Sciences and Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, Florida.
Cecele C QuaintanceDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California.
Ana LabordeDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California.
Lucy KingDepartment of Psychology, Stanford University, Stanford, California.
Ian H GotlibDepartment of Psychology, Stanford University, Stanford, California.
Brice GaudilliereDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California.
Martin S AngstDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California.
Gary M ShawDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California.ORCID 0000-0001-7438-4914
David K StevensonDepartment of Pediatrics, Stanford University School of Medicine, Stanford, California.
Nima AghaeepourDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California.
Firdaus S DhabharDepartment of Psychiatry and Behavioral Sciences and Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, Florida.
Stanford University · USUniversity of Miami · US

Funding

Machine Learning for Integrative Modeling of the Immune System in Clinical SettingsR35GM138353 · NIGMS · STANFORD UNIVERSITY · PI AGHAEEPOUR, NIMA · 2020 to 2024
$2.2M
Stress &UV-induced Squamous Cell CarcinomaR01CA107498 · NCI · STANFORD UNIVERSITY · PI DHABHAR, FIRDAUS S · 2005 to 2010
$1.5M
Effects of Environmental Stimulation and Nurturance on Neural and Endocrine Functions in InfantsR21HD090493 · NICHD · STANFORD UNIVERSITY · PI GOTLIB, IAN H · 2017 to 2018
$432k
The Role of Caregiver Social Processes on Neural and Endocrine Function in InfantsR21MH111978 · NIMH · STANFORD UNIVERSITY · PI GOTLIB, IAN H · 2017 to 2018
$432k
NCI NIH HHS R01 CA107498NICHD NIH HHS R21 HD090493NIGMS NIH HHS R35 GM138353NIMH NIH HHS R21 MH111978
6 · The paper itself

Abstract

objectivesThe aim of the study was to: (1) Identify (early in pregnancy) psychosocial and stress-related factors that predict risk of spontaneous preterm birth (PTB, gestational age <37 weeks); (2) Investigate whether "protective" factors (e.g., happiness/social support) decrease risk; (3) Use the Dhabhar Quick-Assessment Questionnaire for Stress and Psychosocial Factors (DQAQ-SPF) to rapidly quantify harmful or protective factors that predict increased or decreased risk respectively, of PTB. STUDY

designThis is a prospective cohort study. Relative risk (RR) analyses investigated association between individual factors and PTB. Machine learning-based interdependency analysis (IDPA) identified factor clusters, strength, and direction of association with PTB. A nonlinear model based on support vector machines was built for predicting PTB and identifying factors that most strongly predicted PTB.

resultsHigher levels of deleterious factors were associated with

conclusionThese findings represent an important step toward identifying key factors, which can be assessed rapidly before/after conception, to predict risk of PTB, and perhaps other adverse pregnancy outcomes. Quantifying these factors, before, or early in pregnancy, could identify women at risk of delivering preterm, pinpoint mechanisms/targets for intervention, and facilitate the development of interventions to prevent PTB. KEY POINTS: · Newly designed questionnaire used for rapid quantification of stress and psychosocial factors early during pregnancy.. · Deleterious factors predict increased preterm birth (PTB) risk.. · Protective factors predict decreased PTB risk..

Indexed as

Premature BirthFemaleGestational AgeHumansInfantInfant, NewbornPainPregnancyPregnancy OutcomeProspective StudiesRisk Factors

Identifiers

PMID34015838
PMCPMC11036409
OpenAlexW3163519437

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.