ArticleBrain, behavior, and immunity2021
Socioeconomic status, financial stress, and glucocorticoid resistance among youth with asthma: Testing the moderation effects of maternal involvement and warmth.
Article in Brain, behavior, and immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- The impact of tangeretin combined with whey protein on exercise-induced bronchoconstriction in professional athletes: a placebo-controlled trial.Journal of the International Society of Sports Nutrition · 2024Trial
- Trial
- Prevalence of exercise-induced bronchoconstriction in elite Chinese summer sport athletes.Journal of sport and health science · 2026Article
- Pathways from neighborhood adversity to life satisfaction among older African American adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Stress, positive affect, and sleep in older African American adults: a test of the stress buffering hypothesis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2025Article
- Age and Sex Differences in the Associations Among Socioeconomic Status, Affective Reactivity to Daily Stressors, and Physical Health in the MIDUS Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Article
- Socioeconomic disadvantage, chronic stress, and proinflammatory phenotype: an integrative data analysis across the lifecourse.PNAS nexus · 2022Article
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
objectivesChildren who grow up in more socioeconomically disadvantaged homes experience greater levels of inflammation and worse asthma symptoms than children from more advantaged families. However, recent evidence suggests that certain family-level factors can mitigate health disparities associated with socioeconomic status (SES). In a sample of youth with asthma, we investigated the potential buffering effects of maternal involvement and warmth on SES disparities in asthma-related immune responses, assessed via glucocorticoid resistance (GR) of immune cells.
methodsOne hundred and forty-three youth (10-16 years of age) with asthma completed measures of maternal involvement and warmth, and their primary caregivers reported their levels of education, income, and financial stress. Peripheral blood mononuclear cells from youth's blood were isolated, cultured, and assayed to determine mitogen-stimulated (PMA/INO + Etho) and mitogen/hydrocortisone-stimulated (PMA/INO + Cort) levels of two Th-2 cytokines (i.e., interleukin-5, interleukin-13) and one Th-1 cytokine (i.e., interferon-γ). GR was calculated by subtracting log-transformed cytokine concentration in the PMA/INO + Etho samples from log-transformed cytokine concentration in the PMA/INO + Cort samples.
resultsBoth maternal involvement and warmth moderated the indirect pathway from family SES to GR of Th-2 cytokines via financial stress. Specifically, we found that low family SES was associated with elevated GR of Th-2 cytokines via increased financial stress among youth reporting low levels of maternal involvement and warmth, but not among those reporting high levels of maternal involvement or warmth.
conclusionsThese results highlight the protective role of maternal involvement and warmth in health-related biological processes modulated by family SES among youth with asthma.
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