ReviewIntestinal research2022
The role of microbiome in colorectal carcinogenesis and its clinical potential as a target for cancer treatment.
Review in Intestinal research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 47 citations in OpenAlex.
- Instance-based transfer learning enables cross-cohort early detection of colorectal cancer.NPJ biofilms and microbiomes · 2026Article
- Gut microbiota and neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a review of current evidence and emerging insights.Therapeutic advances in medical oncology · 2026Review
- Exploring the clinical value of probiotics in the perioperative management of colorectal cancer: Meta-analysis with trial sequential analysis.Oncology letters · 2025Article
- Role of gut microbiome in colorectal cancer: a comprehensive umbrella review protocol.BMJ open · 2025Article
- Gastrointestinal tract, its pathophysiology andWorld journal of gastroenterology · 2025Review
- Effect of Probiotics on Improving Intestinal Mucosal Permeability and Inflammation after Surgery.Gut and liver · 2025Article
- Benchmarking and optimizing microbiome-based bioinformatics workflow for non-invasive detection of intestinal tumors.Microbiome research reports · 2025Article
- A New Combination ofFoods (Basel, Switzerland) · 2024Article
- Immunomodulation aspects of gut microbiome-related interventional strategies in colorectal cancer.Medical oncology (Northwood, London, England) · 2024Review
- Forces at play: exploring factors affecting the cancer metastasis.Frontiers in immunology · 2024Review
- Comments on Efficacy of a Synbiotic ContainingGut and liver · 2023Article
- [Calcium, Vitamin D, and Colorectal Cancer].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023Review
- Impact of Diet on Colorectal Cancer Progression and Prevention: From Nutrients to Neoplasms.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023Review
- [Gut Microbiome and Colorectal Cancer].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023Review
- Probiotic-Derived Bioactive Compounds in Colorectal Cancer Treatment.Microorganisms · 2023Review
- Olfactomedin 4 produces dysplasia but suppresses metastasis of colon cancer.Cancer gene therapy · 2023Article
- Article
- Comment on " Positive fecal immunochemical test results are associated with non-colorectal cancer mortality".The Korean journal of internal medicine · 2023Article
- The role of microbiomes in gastrointestinal cancers: new insights.Frontiers in oncology · 2023Review
- Cancer Immunotherapy: Fecal Microbiota Transplantation Brings Light.Current treatment options in oncology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of gut microbiome-intestinal immune complex in the development of colorectal cancer and its progression is well recognized. Accordingly, certain microbial strains tend to colonize or vanish in patients with colorectal cancer. Probiotics, prebiotics, and synbiotics are expected to exhibit both anti-tumor effects and chemopreventive effects during cancer treatment through mechanisms such as xenometabolism, immune interactions, and altered eco-community. Microbial modulation can also be safely used to prevent complications during peri-operational periods of colorectal surgery. A deeper understanding of the role of intestinal microbiota as a target for colorectal cancer treatment will lead the way to a better prognosis for colorectal cancer patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.