Evidence map›Paper›PMID 34015146›Full record

ReviewLasers in surgery and medicine2021

Deep Learning in Biomedical Optics.

Lei Tian, Brady Hunt, Muyinatu A Lediju Bell, Ji Yi, Jason T Smith, Marien Ochoa, Xavier Intes, Nicholas J Durr

Abstract readReview
In one paragraph

Review in Lasers in surgery and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Deep Learning to Localize Photoacoustic Sources in Three Dimensions: Theory and Implementation.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Model-Based Explainable Deep Learning for Light-Field Microscopy Imaging.IEEE transactions on image processing : a publication of the IEEE Signal Processing Society · 2024
    Article
  19. Deep learningJournal of biomedical optics · 2024
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Lei TianDepartment of Electrical and Computer Engineering, Boston University, 8 St. Mary's Street, RM 830, Boston, Massachusetts, 02215.ORCID 0000-0002-1316-4456
Brady HuntThayer School of Engineering, Dartmouth College, Hanover, New Hampshire, 03755.
Muyinatu A Lediju BellDepartment of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, 21218.
Ji YiDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, 21218.
Jason T SmithCenter for Modeling, Simulation, and Imaging in Medicine, Rensselaer Polytechnic Institute, Troy, New York, 12180.
Marien OchoaCenter for Modeling, Simulation, and Imaging in Medicine, Rensselaer Polytechnic Institute, Troy, New York, 12180.
Xavier IntesCenter for Modeling, Simulation, and Imaging in Medicine, Rensselaer Polytechnic Institute, Troy, New York, 12180.
Nicholas J DurrDepartment of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, 21218.

Funding

Role of tumor heterogeneity on receptor engagementR01CA207725 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, CORR, DAVID THOMAS · 2017 to 2021
$3.0M
In vivo Macroscopic Fluorescence Lifetime Molecular Optical ImagingR01CA250636 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, INTES, XAVIER · 2020 to 2023
$2.9M
Photon-counting X-ray and Optical Tomography for Preclinical Cancer ResearchR01CA237267 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, INTES, XAVIER · 2019 to 2023
$2.9M
Predictive markers for diabetic retinopathy via quantitative imaging of retinal capillary functionsR01NS108464 · NINDS · JOHNS HOPKINS UNIVERSITY · PI YI, JI · 2018 to 2022
$2.5M
A novel method for volumetric oxygen mapping in living retinaR01EY032163 · NEI · JOHNS HOPKINS UNIVERSITY · PI YI, JI · 2021 to 2024
$2.0M
Time-Resolved Wide-Field Molecular Optical TomographyR01EB019443 · NIBIB · RENSSELAER POLYTECHNIC INSTITUTE · PI INTES, XAVIER · 2015 to 2018
$1.7M
A Machine Learning Alternative to Beamforming to Improve Ultrasound Image Quality for Interventional Access to the KidneyR21EB025621 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI BELL, MUYINATU A. LEDIJU · 2018 to 2021
$859k
Quantitative topographic endoscopy for improved screening of non-polypoid colorectal neoplasmsR21EB024700 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI DURR, NICHOLAS JAMES · 2018 to 2019
$623k
Sensitive detection of malignancy in primary acquired melanosis by advanced optical imagingR21EY029412 · NEI · JOHNS HOPKINS UNIVERSITY · PI LEE, HYUNJOO JEAN, YI, JI · 2018 to 2019
$456k
NCI NIH HHS R01 CA207725NCI NIH HHS R01 CA237267NCI NIH HHS R01 CA250636NEI NIH HHS R01 EY032163NEI NIH HHS R21 EY029412NIBIB NIH HHS R01 EB019443NIBIB NIH HHS R21 EB024700NIBIB NIH HHS R21 EB025621NIH HHS R01CA207725NIH HHS R01CA237267NIH HHS R01CA250636NIH HHS R01EB019443NIH HHS R01NS108464NIH HHS R21EB024700NIH HHS R21EB025621NINDS NIH HHS R01 NS108464
6 · The paper itself

Abstract

This article reviews deep learning applications in biomedical optics with a particular emphasis on image formation. The review is organized by imaging domains within biomedical optics and includes microscopy, fluorescence lifetime imaging, in vivo microscopy, widefield endoscopy, optical coherence tomography, photoacoustic imaging, diffuse tomography, and functional optical brain imaging. For each of these domains, we summarize how deep learning has been applied and highlight methods by which deep learning can enable new capabilities for optics in medicine. Challenges and opportunities to improve translation and adoption of deep learning in biomedical optics are also summarized. Lasers Surg. Med. © 2021 Wiley Periodicals LLC.

Indexed as

Deep LearningMicroscopyOptical ImagingOptics and PhotonicsTomography, Optical Coherencebiomedical opticsbiophotonicscomputer aided detectiondeep learningdiffuse tomographyfluorescence lifetimefunctional optical brain imagingin vivo microscopymachine learningmicroscopyoptical coherence tomographyphotoacoustic imagingwidefield endoscopy

Identifiers

PMID34015146
PMCPMC8273152

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.