Evidence map›Paper›PMID 34015084›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2021

Antibiotic Utilization in Deceased Organ Donors.

Judith A Anesi, Ebbing Lautenbach, Jennifer Han, Dong Heun Lee, Heather Clauss, Antonette Climaco, Richard Hasz, Warren B Bilker, Esther Molnar, Darcy Alimenti and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. The Next Generation: Mentoring and Diversity in the Antibacterial Resistance Leadership Group.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Judith A AnesiDivision of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ebbing LautenbachDivision of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jennifer HanGlaxoSmithKline, Rockville, Maryland, USA.
Dong Heun LeeDivision of Infectious Diseases, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Heather ClaussSection of Infectious Diseases, Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Antonette ClimacoDivision of Infectious Diseases, Department of Medicine, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA.
Richard HaszGift of Life Donor Program, Philadelphia, Pennsylvania, USA.
Warren B BilkerCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Esther MolnarSection of Infectious Diseases, Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Darcy AlimentiDivision of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sharon WestGift of Life Donor Program, Philadelphia, Pennsylvania, USA.
Pam TolomeoCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Emily A BlumbergDivision of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USGift of Life Michigan · USTemple University · USEinstein Medical Center Philadelphia · USGlaxoSmithKline (United States) · USUniversity of California, San Francisco · US

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
Mentoring and patient-oriented research in antimicrobial resistanceK24AI080942 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI LAUTENBACH, EBBING · 2009 to 2013
$853k
Impact of donor bacterial infections on solid organ transplant recipient outcomesK01AI137317 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ANESI, JUDITH · 2019 to 2023
$722k
NCEZID CDC HHS U54 CK000485NIAID NIH HHS K01 AI137317NIAID NIH HHS K24 AI080942NIAID NIH HHS UM1 AI104681
6 · The paper itself

Abstract

Antibiotic use in deceased organ donors has not been previously described. In a retrospective cohort of 440 donors, we found 427 (97%) received at least one antibiotic course, 312 (71%) received broad-spectrum antibiotics, and 61 (14%) received potentially redundant antibiotics during their terminal hospitalization, suggesting a need for stewardship.

Indexed as

Anti-Bacterial AgentsTissue and Organ ProcurementHumansRetrospective StudiesRisk FactorsTissue DonorsAnti-Bacterial Agentsantibioticdonorstewardshiptransplant

Identifiers

PMID34015084
PMCPMC8561239
OpenAlexW3160014963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.