Evidence map›Paper›PMID 34014930›Full record

ArticlePLoS neglected tropical diseases2021

Whole-genome sequencing and phylogenetic analysis of rabies viruses from Jordan.

Laith N Al-Eitan, Guanghui Wu, Megan Golding, Yue Tang, Hooman Goharriz, Denise A Marston, Anthony R Fooks, Lorraine M McElhinney

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Laith N Al-EitanDepartment of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0003-0064-0190
Guanghui WuAnimal and Plant Health Agency (APHA, Weybridge), Surrey, United Kingdom.
Megan GoldingAnimal and Plant Health Agency (APHA, Weybridge), Surrey, United Kingdom.
Yue TangAnimal and Plant Health Agency (APHA, Weybridge), Surrey, United Kingdom.ORCID 0000-0001-9638-8270
Hooman GoharrizAnimal and Plant Health Agency (APHA, Weybridge), Surrey, United Kingdom.
Denise A MarstonAnimal and Plant Health Agency (APHA, Weybridge), Surrey, United Kingdom.ORCID 0000-0001-9215-088X
Anthony R FooksAnimal and Plant Health Agency (APHA, Weybridge), Surrey, United Kingdom.ORCID 0000-0002-3243-6154
Lorraine M McElhinneyAnimal and Plant Health Agency (APHA, Weybridge), Surrey, United Kingdom.ORCID 0000-0002-6022-348X
Animal and Plant Health Agency · GBJordan University of Science and Technology · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human fatalities caused by rabies are rarely reported in Jordan; however, domestic animals are more likely to fall victim to rabies compared to wild animals, at least this is the case in Jordan due to the presence of canine rabies. In this study, twelve brain samples from domestic and wild animals suspected of being infected with rabies virus from different regions of Jordan were collected during 2019. Seven of them tested positive using the fluorescent antibody test and real-time SYBR RT-PCR assay. Five specimens were from stray dogs and two from foxes. The whole genome sequences were obtained from the positive samples. Sequence analysis showed that one dog virus from Al Quwaysimah city located in Amman governorate, was closely related to an Israeli strain belonging to a Cosmopolitan ME1a clade. The genomes of the remaining six viruses (four from dogs and two from foxes) collected from different areas of Jordan were genetically-related to each other and clustered together with sequences from Iran and Turkey; all belong to Cosmopolitan ME2 clade. These sequences were analyzed with six other Jordanian rabies virus nucleoprotein (N) gene sequences available in the public database, five of them belong to ME1a clade and one belongs to ME1b clade. Rabies virus whole genome data is scarce across the Middle East. This study provides a better understanding of the molecular epidemiology of rabies virus in the region.

Indexed as

AnimalsBrainDog DiseasesDogsFoxesJordanMolecular EpidemiologyPhylogenyRabiesRabies virusWhole Genome Sequencing

Identifiers

PMID34014930
PMCPMC8171950
OpenAlexW3160827355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.