Evidence map›Paper›PMID 34014780›Full record

ArticleThe neuroradiology journal2021

High-resolution vessel wall imaging after mechanical thrombectomy.

Sami Al Kasab, Girish Bathla, Alberto Varon, Jorge A Roa, Ryan Sabotin, Ashrita Raghuram, Wu Chaorong, David M Hasan, Tanya N Turan, Rano Chatterjee and 1 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in The neuroradiology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05907629 (Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05907629 recruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging

TypeobservationalSponsorYale UniversityRan2024 to 2029Enrolled300ConditionsStroke, Intracranial Atherosclerotic Stenosis (ICAS)ArmsMRI
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Adhesion of vessel wall to stentriever during combined technique for mechanical thrombectomy in acute ischemic stroke: A histomorphological study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  2. Article
  3. Observational
  4. Is first-pass effect a meaningful metric to evaluate thrombectomy technologies?Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sami Al KasabDepartment of Neurology, Medical University of South Carolina,USA.
Girish BathlaDepartment of Radiology, University of Iowa Hospitals and Clinics,USA.
Alberto VaronDepartment of Neurology, University of Iowa Hospitals and Clinics, USA.ORCID https://orcid.org/0000-0001-8447-4067
Jorge A RoaDepartment of Neurology, University of Iowa Hospitals and Clinics, USA.
Ryan SabotinDepartment of Neurology, University of Iowa Hospitals and Clinics, USA.
Ashrita RaghuramDepartment of Neurology, University of Iowa Hospitals and Clinics, USA.
Wu ChaorongInstitute for Clinical and Translational Science, University of Iowa, USA.
David M HasanDepartment of Neurosurgery, University of Iowa Hospitals and Clinics, USA.
Tanya N TuranDepartment of Neurology, Medical University of South Carolina,USA.
Rano ChatterjeeDepartment of Radiology, Washington University in St Louis, USA.
Edgar A SamaniegoDepartment of Radiology, University of Iowa Hospitals and Clinics,USA.ORCID https://orcid.org/0000-0003-2764-2268
University of Iowa Hospitals and Clinics · USMedical University of South Carolina · USUniversity of Iowa · USWashington University in St. Louis · US

Funding

The University of Iowa Clinical and Translational Science AwardUL1TR002537 · NCATS · UNIVERSITY OF IOWA · PI HANSEN, MARLAN R, WINOKUR, PATRICIA · 2018 to 2022
$20.0M
NCATS NIH HHS UL1 TR002537
6 · The paper itself

Abstract

objectivesHigh-resolution magnetic resonance imaging has the potential of characterising arterial wall changes after endovascular mechanical thrombectomy. The purpose of this study is to evaluate high-resolution magnetic resonance imaging features of large intracranial arteries following mechanical thrombectomy.

methodsPatients who presented with acute ischaemic stroke due to large vessel occlusion and underwent mechanical thrombectomy were prospectively recruited. Subjects underwent high-resolution magnetic resonance imaging within 24 hours of the procedure. Magnetic resonance imaging sequences included whole brain T1 pre and post-contrast black-blood imaging, three-dimensional T2, contrast-enhanced magnetic resonance angiography and susceptibility-weighted imaging. Arterial wall enhancement was objectively assessed after normalisation with the pituitary stalk. The contrast ratio of target vessels was compared with non-affected reference vessels.

resultsTwenty patients with 22 target vessels and 20 reference vessels were included in the study. Sixteen patients were treated with stentriever with or without aspiration, and four with contact aspiration only. Significantly higher arterial wall enhancement was identified on the target vessel when compared to the reference vessel (U = 22.5,

conclusionsThis prospective pilot study used the objective quantification of arterial wall enhancement in determining arterial changes after mechanical thrombectomy. Preliminary data suggest that the use of stentrievers is associated with a higher enhancement as compared to reperfusion catheters.

Indexed as

Brain IschemiaStrokeHumansPilot ProjectsProspective StudiesThrombectomycontact aspirationendothelial damageMechanical thrombectomysignal intensitystroke

Identifiers

PMID34014780
PMCPMC8649198
OpenAlexW3162160878

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.