Evidence map›Paper›PMID 34014488›Full record

ArticleNeurochemical research2021

Role of TRPV4-P2X7 Pathway in Neuropathic Pain in Rats with Chronic Compression of the Dorsal Root Ganglion.

Xiaohua Fan, Chuanwei Wang, Junting Han, Xinli Ding, Shaocan Tang, Liping Ning

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  13. Electro-acupuncture modulated miR-214 expression to prevent chondrocyte apoptosis and reduce pain by targeting BAX and TRPV4 in osteoarthritis rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024
    Article
  14. Review
  15. Acute Toxicity and Pharmacokinetic Profile of an EU-GMP-CertifiedPharmaceuticals (Basel, Switzerland) · 2023
    Article
  16. Article
  17. The role of TRPV4 channels in cutaneous epithelia.Current topics in membranes · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xiaohua FanDepartment of Rehabilitation Medicine, Shandong Provincial Hospital, 324 Jing Wu Wei Qi Road, Jinan, 250012, China.
Chuanwei WangDepartment of Neurosurgery, Qilu Hospital Affiliated To Shandong University, 44 West Wenhua Road, Jinan, 250012, China.
Junting HanDepartment of Rehabilitation Medicine, Shandong First Medical University, Taian, 250012, China.
Xinli DingDepartment of Rehabilitation Medicine, Shandong Provincial Hospital, 324 Jing Wu Wei Qi Road, Jinan, 250012, China.
Shaocan TangDepartment of Rehabilitation Medicine, Shandong Provincial Hospital, 324 Jing Wu Wei Qi Road, Jinan, 250012, China.
Liping NingDepartment of Rehabilitation Medicine, Shandong Provincial Hospital, 324 Jing Wu Wei Qi Road, Jinan, 250012, China. sabrinanlp@126.com.ORCID http://orcid.org/0000-0002-7600-7159
Shandong Provincial Hospital · CNQilu Hospital of Shandong University · CNTaishan Medical University · CN

Funding

National Natural Science Foundation of China 81401868National Natural Science Foundation of China 81502148Shandong Province Medical and Health Science and Technology Development Project 2017WS468Teaching reform and research project of undergraduate education in Clinical Medicine College of Shandong University LCJY-72
6 · The paper itself

Abstract

Transient receptor potential vanilloid 4 (TRPV4) is a Ca

Indexed as

AnimalsGanglia, SpinalHyperalgesiaLeucineMaleMorpholinesNerve Compression SyndromesNeuralgiaPurinergic P2X Receptor AntagonistsPyrrolesRatsRats, WistarReceptors, Purinergic P2X7Rosaniline DyesSignal TransductionSulfonamidescoomassie Brilliant BlueHC-067047LeucineMorpholinesN-(1-((4-(2-(((2,4-dichlorophenyl)sulfonyl)amino)-3-hydroxypropanoyl)-1-piperazinyl)carbonyl)-3-methylbutyl)-1-benzothiophene-2-carboxamidePurinergic P2X Receptor AntagonistsPyrrolesReceptors, Purinergic P2X7RN 1734Rosaniline DyesSulfonamidesTrpv4 protein, ratTRPV Cation ChannelsCCDNeuropathic painP2X7 receptorTRPV4 channel

Identifiers

PMID34014488
OpenAlexW3161564536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.