Evidence map›Paper›PMID 34014461›Full record

ArticleInternational ophthalmology2021

Combined Ab interno viscocanaloplasty (ABiC) in open-angle glaucoma: 12-month outcomes.

Kevin Gillmann, Amr Aref, Laëtitia Jessy Niegowski, Jean-Marc Baumgartner

Abstract read
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In one paragraph

Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
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  6. Visual Function After Schlemm's Canal-Based MIGS.Journal of clinical medicine · 2025
    Review
  7. Real-World Outcomes of Combined Phacoemulsification and STREAMLINEClinical ophthalmology (Auckland, N.Z.) · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
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  15. Interim Analysis of STREAMLINEClinical ophthalmology (Auckland, N.Z.) · 2022
    Article
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  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Kevin GillmannOphthalmology Network Organisation, Clinique de L'Oeil SA, Avenue Bois-de-la-Chapelle 35, 1213, Onex, Geneva, Switzerland. kevin.gillmann@wanadoo.fr.ORCID http://orcid.org/0000-0002-7856-6253
Amr ArefResearch Institute of Ophthalmology, Giza, Egypt.
Laëtitia Jessy NiegowskiOphthalmology Network Organisation, Clinique de L'Oeil SA, Avenue Bois-de-la-Chapelle 35, 1213, Onex, Geneva, Switzerland.
Jean-Marc BaumgartnerOphthalmology Network Organisation, Clinique de L'Oeil SA, Avenue Bois-de-la-Chapelle 35, 1213, Onex, Geneva, Switzerland.
Research Institute of Ophthalmology · EGWest African Health Organisation · BF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to analyse the safety profile and efficacy of ab interno viscocanaloplasty (ABiC) through to 12 months post-operatively.

methodsIn this retrospective study, the medical records of all patients who underwent ABiC between September 2015 and December 2019 were analysed. Complete success was defined as a 12-month reduction in intraocular pressure (IOP) ≥ 20% from baseline with no concomitant medications. Qualified success criteria were identical, with no more medications than at baseline.

resultsIn all, 54 eyes of 41 patients were analysed. Mean IOP decreased from 23.6 ± 7.4 mmHg preoperatively to 14.2 ± 2.9 mmHg (-39.8%; p < 0.001) after 12 months. Concomitantly, the number of anti-glaucoma treatment dropped from 2.9 ± 1.0 to 0.6 ± 1.1 (-79.3%; p < 0.001). Amongst patients with a baseline MD < -12.0 dBs, mean IOP decreased from 22.8 ± 9.8 mmHg to 13.8 ± 4.4 mmHg (p = 0.049), with a concomitant reduction of medications from 2.8 ± 1.3 to 1.2 ± 1.3 (p < 0.001). Complete success at 12 months was achieved in 46% of eyes, and qualified success was achieved in 65% of eyes. Amongst eyes with a baseline MD < -12.0 dBs, 50% achieved complete success, and 83.3% achieved qualified success. A total of 19 eyes (35.2%) were considered surgical failure, all due to uncontrolled IOP. Of them, 7 eyes (13.0%) required further filtering surgery. Twelve post-operative adverse events were observed, with early post-operative IOP spikes being the most common (22.2%).

conclusionsABIC achieved a statistically significant reduction in IOP and anti-glaucoma medications through 12 months, while maintaining a favourable safety profile in mild-to-severe open-angle glaucoma.

Indexed as

Glaucoma, Open-AngleTrabeculectomyHumansIntraocular PressureRetrospective StudiesTonometry, OcularTreatment OutcomeCanaloplastyGlaucomaiTrackMIGSSurgeryViscocanalostomy

Identifiers

PMID34014461
OpenAlexW3162283721

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.