Evidence map›Paper›PMID 34014446›Full record

ReviewCurrent HIV/AIDS reports2021

Interventions Addressing Depression and HIV-Related Outcomes in People with HIV.

Noelle A Mendez, Daniel Mayo, Steven A Safren

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Noelle A MendezDepartment of Psychology, University of Miami, Coral Gables, FL, USA.ORCID https://orcid.org/0000-0001-5920-4196
Daniel MayoDepartment of Psychology, University of Miami, Coral Gables, FL, USA.ORCID https://orcid.org/0000-0002-5826-3589
Steven A SafrenDepartment of Psychology, University of Miami, Coral Gables, FL, USA. ssafren@miami.edu.ORCID http://orcid.org/0000-0002-0121-0806
University of Miami · US

Funding

The University of Miami AIDS Research Center on Mental Health and HIV/AIDS - Center for HIV & Research in Mental Health (CHARM)Research Core & MHD-CEP30MH133399 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI Victoria Behar-Zusman · 2023 to 2026
$8.9M
University of Miami Developmental HIV/AIDS Mental Health Research Center (D-ARC)P30MH116867 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2019 to 2023
$6.5M
Nurse-Delivered CBT for Depression-Adherence in HIV Primary Care S. AfricaR01MH103770 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI O'CLEIRIGH, CONALL MICHAEL, SAFREN, STEVEN A · 2015 to 2019
$3.1M
Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
NIDA NIH HHS K24 DA040489NIMH NIH HHS P30 MH116867NIMH NIH HHS P30 MH133399NIMH NIH HHS R01 MH103770
6 · The paper itself

Abstract

purpose of reviewPeople with HIV (PWH) are more likely to experience depression than those without HIV. Depression is not only distressing and interfering in and of itself, but it is also consistently associated with non-adherence to antiretroviral treatment (ART). Accordingly, research and clinical priorities require updated knowledge about interventions that address depression in PWH. RECENT

findingsTwenty efficacy trials and nine pilot studies since a 2009 review emerged in the literature review search. Of these, 11 and 6 respectively had a depression-related inclusion criterion. The intervention strategies included individual psychotherapy (n=6), group therapy (n=6), telehealth (n=3), and antidepressant medication (n=5). Generally, these interventions demonstrated acute efficacy for improving depression symptoms in PWH, with some also addressing ART non-adherence. However, not all studies collected follow-up data. Furthermore, trials that addressed depression but did not specifically address non-adherence did not also show adherence improvements. Existing interventions for depression have demonstrated efficacy in PWH, and these may have both positive mental and physical health outcomes. Future trials should measure and boost longer-term effects. It would be useful to incorporate adherence interventions into depression treatment to improve self-care behaviors and health outcomes.

Indexed as

DepressionHIV InfectionsAnti-Retroviral AgentsHumansMedication AdherenceAnti-Retroviral AgentsART adherenceDepressionHIVIntervention

Identifiers

PMID34014446
PMCPMC8136266
OpenAlexW3162250599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.