Evidence map›Paper›PMID 34014421›Full record

ArticleCellular and molecular neurobiology2022

Divergent Dimethylarginine Dimethylaminohydrolase Isoenzyme Expression in the Central Nervous System.

Alena A Kozlova, Vinitha N Ragavan, Natalia Jarzebska, Iana V Lukianova, Anastasia E Bikmurzina, Elena Rubets, Toshiko Suzuki-Yamamoto, Masumi Kimoto, Arduino A Mangoni, Raul R Gainetdinov and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. The Emerging Role of the DDAH Proteins in Psychiatric Disorders.Biological psychiatry global open science · 2025
    Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Alena A Kozlova *Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0002-0254-6264
Vinitha N Ragavan *University Centre for Vascular Medicine and Department of Internal Medicine, Technische Universität Dresden, Dresden, Germany.
Natalia JarzebskaUniversity Centre for Vascular Medicine and Department of Internal Medicine, Technische Universität Dresden, Dresden, Germany.
Iana V LukianovaDepartment of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Anastasia E BikmurzinaDepartment of General Physiology, Saint-Petersburg State University, 199034, Saint-Petersburg, Russia.ORCID http://orcid.org/0000-0002-4533-0834
Elena RubetsUniversity Centre for Vascular Medicine and Department of Internal Medicine, Technische Universität Dresden, Dresden, Germany.
Toshiko Suzuki-YamamotoDepartment of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan.ORCID http://orcid.org/0000-0002-0331-9872
Masumi KimotoDepartment of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, Okayama, Japan.
Arduino A MangoniDepartment of Clinical Pharmacology, College of Medicine and Public Health, Flinders University and Flinders Medical Centre, Adelaide, Australia.ORCID http://orcid.org/0000-0001-8699-1412
Raul R GainetdinovInstitute of Translational Biomedicine and Saint-Petersburg University Hospital, Saint-Petersburg State University, Saint-Petersburg, Russia.ORCID http://orcid.org/0000-0003-2951-6038
Norbert WeissUniversity Centre for Vascular Medicine and Department of Internal Medicine, Technische Universität Dresden, Dresden, Germany.
Michael BauerDepartment of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Alexander G MarkovDepartment of General Physiology, Saint-Petersburg State University, 199034, Saint-Petersburg, Russia.ORCID http://orcid.org/0000-0002-2867-044X
Roman N Rodionov *University Centre for Vascular Medicine and Department of Internal Medicine, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0002-7470-7776
Nadine Bernhardt *Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. nadine.bernhardt@uniklinikum-dresden.de.ORCID http://orcid.org/0000-0002-3188-8431
St Petersburg University · RUUniversity Hospital Carl Gustav Carus · DEFlinders University · AUOkayama Prefectural University · JPTechnische Universität Dresden · DE

Funding

German Academic Exchange Service Research scholarshipGerman Foundation of Heart Research F/24/17Gesellschaft von Freunden und Fördern der TU Dresden Research scholarshipMedical Faculty, TU Dresden woman Habilitationstipend 2020/2021Saint Petersburg State University 51143531
6 · The paper itself

Abstract

The endogenous methylated derivative of ʟ-arginine, N

Indexed as

IsoenzymesNitric OxideAmidohydrolasesAnimalsCentral Nervous SystemHumansMiceAmidohydrolasesdimethylargininaseIsoenzymesNitric OxideBrainDDAH1DDAH2HumanMouse

Identifiers

PMID34014421
PMCPMC9418281
OpenAlexW3124570405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.