ArticleBiodegradation2021
The optimization of enzymatic oxidation of levofloxacin, a fluoroquinolone antibiotic for wastetwater treatment.
Article in Biodegradation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 18 citations in OpenAlex.
- Isolation and identification of a novel cellulolytic bacterium and optimization of FPase production for bagasse hydrolysis.Biodegradation · 2025Article
- Bioelectrocatalyst for OInternational journal of molecular sciences · 2025Article
- Article
- Bioremediation of Hazardous Pollutants Using Enzyme-Immobilized Reactors.Molecules (Basel, Switzerland) · 2024Review
- Impact of veterinary pharmaceuticals on environment and their mitigation through microbial bioremediation.Frontiers in microbiology · 2024Review
- Preparation of g-CMicromachines · 2023Article
- Biotransformation of the Fluoroquinolone, Levofloxacin, by the White-Rot FungusJournal of fungi (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global presence of antibiotics in the environment has created concerns about the emergence of antibiotic resistance bacteria and potential hazard to humans and the ecosystem. This work aims to study the removal of levofloxacin, a new generation fluoroquinolone antibiotic from aqueous solutions by enzyme mediated oxidation process and optimization of the conditions thereof by response surface methodology (RSM) using Box-Behnken design (BBD). For this study, experiments were conducted to analyze the effect of independent variables namely, pH, temperature, mediator concentration and antibiotic concentration on the degradation percentage of levofloxacin antibiotic using laccase enzyme derived from Trametes versicolor. The residual levofloxacin concentration was determined using high performance liquid chromatography (HPLC). On applying the quadratic regression analysis, among the main parameters, it was found that the percentage degradation was significantly affected by all the four variables. The predicted values for percentage degradation of levofloxacin were close to the experimental values obtained and the R
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Registered trials
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