Evidence map›Paper›PMID 34014385›Full record

ArticleArchives of virology2021

Complete genome sequence of the newly discovered temperate Clostridioides difficile bacteriophage phiCDKH01 of the family Siphoviridae.

Krzysztof Hinc, Monika Kabała, Adam Iwanicki, Gajane Martirosian, Alessandro Negri, Michał Obuchowski

Open access · hybridAbstract read
In one paragraph

Article in Archives of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Novel insights into phage biology of the pathogenFrontiers in microbiology · 2024
    Article
  5. Review
  6. Detection and Analysis ofInternational journal of environmental research and public health · 2022
    Article
  7. Phage therapy forFrontiers in immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Krzysztof HincDivision of Molecular Bacteriology, Institute of Medical Biotechnology and Experimental Oncology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Dębinki 1, 80-211, Gdańsk, Poland. krzysztof.hinc@biotech.ug.edu.pl.ORCID http://orcid.org/0000-0002-6067-7852
Monika KabałaDepartment of Medical Microbiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medyków 18, 40-752, Katowice, Poland.
Adam IwanickiDivision of Molecular Bacteriology, Institute of Medical Biotechnology and Experimental Oncology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Dębinki 1, 80-211, Gdańsk, Poland.
Gajane MartirosianDepartment of Medical Microbiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medyków 18, 40-752, Katowice, Poland.
Alessandro NegriDivision of Molecular Bacteriology, Institute of Medical Biotechnology and Experimental Oncology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Dębinki 1, 80-211, Gdańsk, Poland.
Michał ObuchowskiDivision of Molecular Bacteriology, Institute of Medical Biotechnology and Experimental Oncology, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Dębinki 1, 80-211, Gdańsk, Poland.
Gdańsk Medical University · PLMedical University of Silesia · PLUniversity of Gdańsk · PL

Funding

Narodowym Centrum Nauki 2018/02/X/NZ6/01360
6 · The paper itself

Abstract

A temperate siphovirus, phiCDKH01, was obtained from a clinical isolate of Clostridioides difficile. The phage genome is a 45,089-bp linear double-stranded DNA molecule with an average G+C content of 28.7%. It shows low similarity to known phage genomes, except for phiCD24-1. Genomic and phylogenetic analysis revealed that phiCDKH01 is a newly discovered phage. Sixty-six putative ORFs were predicted in the genome, 37 of which code for proteins with predicted functions. The phiCDKH01 prophage was localized in the host genome. The results of this study increase our knowledge about the genetic diversity of tailed phages.

Indexed as

Base CompositionClostridioides difficileGenome SizeGenome, ViralOpen Reading FramesPhylogenyProphagesSiphoviridaeWhole Genome Sequencing

Identifiers

PMID34014385
PMCPMC8270841
OpenAlexW3162735079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.