Evidence map›Paper›PMID 34014141›Full record

ArticleOcular immunology and inflammation2022

Understanding Retinal Vasculitis Associated with Brolucizumab: Complex Pathophysiology or Occam's Razor?

Ashish Sharma, Nilesh Kumar, Nikulaa Parachuri, Sonali Singh, Francesco Bandello, Carl D Regillo, David Boyer, Quan Dong Nguyen

Open access · bronzeAbstract readEditorial
In one paragraph

Article in Ocular immunology and inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ashish SharmaLotus Eye Hospital and Institute, Coimbatore, India.ORCID 0000-0002-8550-9791
Nilesh KumarLotus Eye Hospital and Institute, Coimbatore, India.ORCID 0000-0002-7439-2081
Nikulaa ParachuriLotus Eye Hospital and Institute, Coimbatore, India.
Sonali SinghOcular Pathologist, Madhavi Netralaya, Ara, India.
Francesco BandelloScientific Institute San Raffaele, University Vita-Salute, Milano, Italy.ORCID 0000-0003-3238-9682
Carl D RegilloMid Atlantic Retina, The Retina Service of Wills Eye Hospital, Philadelphia, Pennsylvania, USA.
David BoyerRetina Vitreous Associates Medical Group, Los Angeles, California, USA.
Quan Dong NguyenByers Eye Institute, Stanford University, Palo Alto, California, USA.
Retina Vitreous Associates Medical Group · USSmith-Kettlewell Eye Research Institute · USWills Eye Hospital · US

Funding

Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
NEI NIH HHS P30 EY026877
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Retinal VasculitisAntibodies, Monoclonal, HumanizedHumansAntibodies, Monoclonal, HumanizedbrolucizumabBrolucizumabintraocular inflammationocclusive vasculitisretinal vasculitis

Identifiers

PMID34014141
PMCPMC10919544
OpenAlexW3161984972

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.